Performance of a condensed protocol to assess limbic-predominant age-related TDP-43 encephalopathy neuropathologic change.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlad035
Abstract: Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is a dementia-related proteinopathy common in the elderly population. LATE-NC stages 2 or 3 are consistently associated with cognitive impairment. A condensed protocol (CP) for the assessment of… read more here.
Keywords: limbic predominant; age; predominant age; neuropathologic change ... See more keywords
The microvascular extracellular matrix in brains with Alzheimer’s disease neuropathologic change (ADNC) and cerebral amyloid angiopathy (CAA)
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DOI: 10.1186/s12987-020-00219-y
Abstract: Background The microvasculature (MV) of brains with Alzheimer’s disease neuropathologic change (ADNC) and cerebral amyloid angiopathy (CAA), in the absence of concurrent pathologies (e.g., infarctions, Lewy bodies), is incompletely understood. Objective To analyze microvascular density,… read more here.
Keywords: disease neuropathologic; alzheimer disease; change adnc; caa ... See more keywords
Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change
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DOI: 10.1186/s40478-022-01353-4
Abstract: Traumatic brain injury (TBI) is associated with the development of a range of neurodegenerative pathologies, including chronic traumatic encephalopathy (CTE). Current consensus diagnostic criteria define the pathognomonic cortical lesion of CTE neuropathologic change (CTE-NC) as… read more here.
Keywords: pathology; tau; cte; detection ... See more keywords
Impact and Risk Factors of Limbic Predominant Age-Related TDP-43 Encephalopathy Neuropathologic Change in an Oldest-Old Cohort
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DOI: 10.1212/wnl.0000000000201345
Abstract: Background and Objectives Limbic predominant age-related TAR DNA binding protein 43 (TDP-43) encephalopathy neuropathologic change (LATE-NC) is a prevalent degenerative pathology in the oldest-old who are the fastest-growing segment of our population with the highest… read more here.
Keywords: oldest old; limbic predominant; age; pathology ... See more keywords