Neuropeptide Substance P Enhances Inflammation-Mediated Tumor Signaling Pathways and Migration and Proliferation of Head and Neck Cancers
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Surgical Oncology"
DOI: 10.1007/s13193-020-01210-7
Abstract: Head and neck cancers (HNC) are extremely aggressive, highly recurrent, and the sixth most common cancer worldwide. Neuropeptide substance P, along with its primary receptor, neurokinin-1 (NK-1R), is overexpressed in HNC and is a central… read more here.
Keywords: neuropeptide substance; neck cancers; proliferation; migration ... See more keywords
The neuropeptide substance P regulates aldosterone secretion in human adrenals
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16470-8
Abstract: Aldosterone, produced by the adrenals and under the control of plasma angiotensin and potassium levels, regulates hydromineral homeostasis and blood pressure. Here we report that the neuropeptide substance P (SP) released by intraadrenal nerve fibres, stimulates aldosterone… read more here.
Keywords: aldosterone production; aldosterone secretion; neuropeptide substance; aldosterone ... See more keywords
The neuropeptide Substance P facilitates the transition from an inflammatory to proliferation phase‐associated responses in dermal fibroblasts
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Dermatology"
DOI: 10.1111/exd.14573
Abstract: The wound healing process is a product of three successive and overlapping phases of inflammation, proliferation and remodelling. Considerable efforts have been invested in deconstructing the intercellular crosstalk that orchestrates tissue repair, and we investigated… read more here.
Keywords: dermal fibroblasts; neuropeptide substance; wound healing; proliferation ... See more keywords
Anti-Wrinkle Efficacy of Neuropeptide Substance P-Based Hydrogel in Human Volunteers
Sign Up to like & getrecommendations! Published in 2020 at "Cosmetics"
DOI: 10.3390/cosmetics7020037
Abstract: This letter is intended to clarify the clinical effectiveness of neuropeptide substance P (SP) in reducing age-related skin wrinkling. This is the first clinical study to evaluate the efficacy of the topical application of SP… read more here.
Keywords: based hydrogel; anti wrinkle; neuropeptide substance; efficacy ... See more keywords