Design, synthesis and evaluation of the antioxidant and neuroprotective properties of alkyl- and terpenylphenolchlorin conjugates
Sign Up to like & getrecommendations! Published in 2018 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-018-2109-4
Abstract: The new amide conjugates were synthesized from methyl pheophorbide a and its carboxyl derivatives by reactions with aminomethyl derivatives of 2,4-dimethylphenol, 2-isocamphyl-4- methylphenol, 2-bornyl-4-methylphenol, and 2-isobornyl-4-methylphenol. The antioxidant activity of some conjugates was established by… read more here.
Keywords: design synthesis; neuroprotective properties; antioxidant neuroprotective; properties alkyl ... See more keywords
Umbelliferyloxymethyl phosphonate compounds-weakly binding zinc ionophores with neuroprotective properties.
Sign Up to like & getrecommendations! Published in 2021 at "Dalton transactions"
DOI: 10.1039/d1dt02298a
Abstract: Umbelliferone is a member of the coumarin family of compounds which are known for diverse pharmacological activity including in targets relevant to Alzheimers disease, AD. The toxicity associated with some forms of the amyloid protein,… read more here.
Keywords: neuroprotective properties; weakly binding; umbelliferyloxymethyl phosphonate; phosphonate compounds ... See more keywords
Neuroprotective properties of solanum leaves in transgenic Drosophila melanogaster model of Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2022 at "Biomarkers"
DOI: 10.1080/1354750x.2022.2077446
Abstract: Abstract Introduction We investigated the effect of African eggplant (AE) (Solanum macrocarpon L) and Black nightshade (BN) (Solanum nigrum L) leaves; two tropical vegetables consumed by humans on behavioural, biochemical and histological indices in Drosophila… read more here.
Keywords: model alzheimer; alzheimer disease; neuroprotective properties; melanogaster model ... See more keywords
Neuroprotective properties of Ferulic acid in preclinical models of Alzheimer's disease: A systematic literature review.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220906110506
Abstract: BACKGROUND Alzheimer's disease (AD) is one of the most common diseases in the elderly, with a high incidence of dementia. The pathogenesis of AD is complex, and there is no unified conclusion and effective treatment… read more here.
Keywords: review; alzheimer disease; neuroprotective properties; treatment ... See more keywords
Neuroprotective properties of antiepileptics: what are the implications for psychiatric disorders?
Sign Up to like & getrecommendations! Published in 2023 at "Current medicinal chemistry"
DOI: 10.2174/0929867330666230523155728
Abstract: Since the discovery of the first antiepileptic compound, increasing attention has been paid to antiepileptic drugs (AEDs), and recently, with the understanding of the molecular mechanism underlying cells death, a new interest has revolved around… read more here.
Keywords: implications psychiatric; psychiatric disorders; chemistry; neuroprotective properties ... See more keywords
Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer’s Disease: A Narrative Review
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14183709
Abstract: Alzheimer’s disease (AD) is a progressive degenerative disorder of the central nervous system, characterized by neuroinflammation, neurotransmitter deficits, and neurodegeneration, which finally leads to neuronal death. Emerging evidence highlighted that hyperglycemia and brain insulin resistance… read more here.
Keywords: narrative review; alzheimer disease; ferulic acid; neuroprotective properties ... See more keywords