Neuroprotective Role of Quercetin on Rotenone-Induced Toxicity in SH-SY5Y Cell Line Through Modulation of Apoptotic and Autophagic Pathways
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemical Research"
DOI: 10.1007/s11064-020-03061-8
Abstract: The detrimental impact on the food chain due to the overuse of rotenone is partly responsible for alpha-synuclein (α-syn) mediated neurotoxicity. It is hypothesized that rotenone overdose leads to cytosolic proteopathy resulting in modulation of… read more here.
Keywords: rotenone; autophagic pathways; quercetin; rotenone induced ... See more keywords
The Neuroprotective Role of Neuroserpin in Ischemic and Hemorrhagic Stroke
Sign Up to like & getrecommendations! Published in 2020 at "Current Neuropharmacology"
DOI: 10.2174/1570159x18666201008113052
Abstract: Tissue plasminogen activator (tPA) is commonly used to treat acute ischemic stroke within an appropriate therapeutic window. Its inhibitor, neuroserpin (NSP), is reported to exhibit neuroprotective effects on stroke. This review aims to summarize, from… read more here.
Keywords: hemorrhagic stroke; role; neuroprotective role; ischemic hemorrhagic ... See more keywords
Neuroprotective role of phosphoserine in primary open-angle glaucoma patients.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202010_23186
Abstract: OBJECTIVE To evaluate the neuroprotective role of phosphoserine (P-Ser) in primary open-angle glaucoma (POAG) patients and to compare its therapeutic effectiveness to placebo treatment. PATIENTS AND METHODS Fifty-one patients (24 males and 27 females) between… read more here.
Keywords: role phosphoserine; angle glaucoma; glaucoma; open angle ... See more keywords
Oxidative Stress and Cognitive Decline: The Neuroprotective Role of Natural Antioxidants
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DOI: 10.3389/fnins.2021.729757
Abstract: Free- radicals (Oxygen and Nitrogen species) are formed in mitochondria during the oxidative phosphorylation. Their high reactivity, due to not-engaged electrons, leads to an increase of the oxidative stress. This condition affects above all the… read more here.
Keywords: decline neuroprotective; stress; stress cognitive; neuroprotective role ... See more keywords
The Neuroprotective Role of Coenzyme Q10 Against Lead Acetate-Induced Neurotoxicity Is Mediated by Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph16162895
Abstract: Heavy metal exposure, in lead (Pb) particularly, is associated with severe neuronal impairment though oxidative stress mediated by reactive oxygen species, and antioxidants may be used to abolish these adverse effects. This study investigated the… read more here.
Keywords: anti apoptotic; induced neurotoxicity; role coenzyme; coenzyme q10 ... See more keywords
Demystifying the Neuroprotective Role of Neuropeptides in Parkinson’s Disease: A Newfangled and Eloquent Therapeutic Perspective
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094565
Abstract: Parkinson’s disease (PD) refers to one of the eminently grievous, preponderant, tortuous nerve-cell-devastating ailments that markedly impacts the dopaminergic (DArgic) nerve cells of the midbrain region, namely the substantia nigra pars compacta (SN-PC). Even though… read more here.
Keywords: disease; parkinson disease; perspective; demystifying neuroprotective ... See more keywords
On the Neuroprotective Role of Astaxanthin: New Perspectives?
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DOI: 10.3390/md16080247
Abstract: Astaxanthin is a carotenoid with powerful antioxidant and anti-inflammatory activity produced by several freshwater and marine microorganisms, including bacteria, yeast, fungi, and microalgae. Due to its deep red-orange color it confers a reddish hue to… read more here.
Keywords: new perspectives; role astaxanthin; neuroprotective role; astaxanthin new ... See more keywords
The Effects of Statins on Neurotransmission and Their Neuroprotective Role in Neurological and Psychiatric Disorders
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26102838
Abstract: Statins are among the most widely used drug classes in the world. Apart from their basic mechanism of action, which is lowering cholesterol levels, many pleiotropic effects have been described so far, such as anti-inflammatory… read more here.
Keywords: effects statins; pleiotropic effects; statins neurotransmission; neurological psychiatric ... See more keywords