Unexpectedly low rates of neuropsychiatric adverse effects associated with mefloquine repurposed for the treatment of glioblastoma
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DOI: 10.1002/cncr.31961
Abstract: I read with interest the recent report by Maraka et al, which described the results of a phase 1 study of temozolomide together with combinations of repurposed memantine, metformin, and mefloquine for the treatment of… read more here.
Keywords: treatment; study; drug; neuropsychiatric adverse ... See more keywords
Neuropsychiatric adverse effects of HIV antiviral medication
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DOI: 10.1016/j.eurpsy.2017.01.1230
Abstract: Introduction HIV (human immunodeficiency virus) infection is related to several neuropsychiatric complications, such as dementia, encephalopathy, psychosis, as well as, opportunistic infections of the central nervous system (CNS). The discovery of antiretroviral therapy (ART) has… read more here.
Keywords: effects hiv; antiviral medication; hiv antiviral; neuropsychiatric complications ... See more keywords
Does remdesivir have any neuropsychiatric adverse effects?
Sign Up to like & getrecommendations! Published in 2020 at "Irish Journal of Psychological Medicine"
DOI: 10.1017/ipm.2020.67
Abstract: On 1 May 2020, the US Food and Drug Administration issued an emergency use authorisation for remdesivir in the treatment of hospitalised COVID-19 patients (Food and Drug Administration, 2020). Remdesivir is a nucleotide analogue antiviral… read more here.
Keywords: effects remdesivir; drug; adverse effects; neuropsychiatric adverse ... See more keywords
Integrase strand transfer inhibitors and neuropsychiatric adverse events in a large prospective cohort
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DOI: 10.1093/jac/dky497
Abstract: OBJECTIVES To analyse the frequency and causes of treatment discontinuation in patients who were treated with an integrase strand transfer inhibitor (INSTI), with a focus on neuropsychiatric adverse events (NPAEs). METHODS Patients in 18 HIV… read more here.
Keywords: adverse events; strand transfer; discontinuation; integrase strand ... See more keywords
Dolutegravir and neuropsychiatric adverse events: a continuing debate.
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DOI: 10.1097/qad.0000000000001596
Abstract: We read with great interest the series of letters regarding dolutegravir-related neuropsychiatric adverse events (NP-AE) [1–4]. We report, here, our experience in a French cohort, to add on the current debate. Data were obtained from… read more here.
Keywords: adverse events; continuing debate; events continuing; neuropsychiatric adverse ... See more keywords
Neuropsychiatric adverse events of antiepileptic drugs in brain tumour‐related epilepsy: an Italian multicentre prospective observational study
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DOI: 10.1111/ene.13375
Abstract: We assessed the prevalence and magnitude of neuropsychiatric adverse events (NPAEs) associated with antiepileptic drugs (AEDs) among patients with brain tumour‐related epilepsy (BTRE). read more here.
Keywords: brain tumour; related epilepsy; neuropsychiatric adverse; tumour related ... See more keywords
Prevalence of neuropsychiatric adverse events and associated factors among adult patients on dolutegravir attending Mulago ISS clinic
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DOI: 10.1111/hiv.13428
Abstract: Dolutegravir (DTG) is a second‐generation integrase strand transfer inhibitor that is recommended by the World Health Organization as the preferred first‐line and second‐line antiretroviral therapy (ART) in patients with HIV. In 2018, Uganda started using… read more here.
Keywords: associated factors; among adult; line; adverse events ... See more keywords
Effect of Valerian in Preventing Neuropsychiatric Adverse Effects of Efavirenz in HIV-Positive Patients: A Pilot Randomized, Placebo-Controlled Clinical Trial
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DOI: 10.1177/1060028017696105
Abstract: Background: Several neuropsychiatric adverse effects of efavirenz are known. Preventing these adverse effects may improve patients’ adherence to antiretroviral therapy (ART). Objectives: To evaluate the efficacy and safety of valerian in preventing neuropsychiatric adverse effects… read more here.
Keywords: effects efavirenz; positive patients; neuropsychiatric adverse; placebo ... See more keywords
Neuropsychiatric adverse drug reactions in children initiated on montelukast in real-life practice
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DOI: 10.1183/13993003.02135-2017
Abstract: We thank Eduardo Urdaneta, from Merck & Co., Inc., for his correspondence regarding our paper [1] and appreciate the opportunity to reply to his concern. read more here.
Keywords: children initiated; drug reactions; reactions children; initiated montelukast ... See more keywords