Identification of Neuropsychiatric Copy Number Variants in a Health Care System Population
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2020.2159
Abstract: This cohort study evaluates the suitability of including pathogenic copy number variants associated with neuropsychiatric disorders in population screening by determining their prevalence and penetrance and exploring the personal utility of disclosing results. read more here.
Keywords: neuropsychiatric copy; number variants; copy number; identification neuropsychiatric ... See more keywords
Using hiPSCs to model neuropsychiatric copy number variations (CNVs) has potential to reveal underlying disease mechanisms
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research"
DOI: 10.1016/j.brainres.2015.11.009
Abstract: Schizophrenia is a neuropsychological disorder with a strong heritable component; genetic risk for schizophrenia is conferred by both common variants of relatively small effect and rare variants with high penetrance. Genetically engineered mouse models can… read more here.
Keywords: copy number; hipscs model; neuropsychiatric copy; model neuropsychiatric ... See more keywords