Sapap4 deficiency leads to postsynaptic defects and abnormal behaviors relevant to hyperkinetic neuropsychiatric disorder in mice.
Sign Up to like & getrecommendations! Published in 2022 at "Cerebral cortex"
DOI: 10.1093/cercor/bhac123
Abstract: Postsynaptic proteins play critical roles in synaptic development, function, and plasticity. Dysfunction of postsynaptic proteins is strongly linked to neurodevelopmental and psychiatric disorders. SAP90/PSD95-associated protein 4 (SAPAP4; also known as DLGAP4) is a key component… read more here.
Keywords: sapap4; neuropsychiatric disorder; hyperkinetic neuropsychiatric; abnormal behaviors ... See more keywords
Hypersexuality As a Neuropsychiatric Disorder: The Neurobiology and Treatment Options.
Sign Up to like & getrecommendations! Published in 2018 at "Current drug targets"
DOI: 10.2174/1389450118666170321144931
Abstract: Hypersexuality refers to abnormally increased or extreme involvement in any sexual activity. It is clinically challenging, presents trans-diagnostically and there is extensive medical literature addressing the nosology, pathogenesis and neuropsychiatric aspects in this clinical syndrome.… read more here.
Keywords: neuropsychiatric disorder; hypersexuality; hypersexuality neuropsychiatric; disorder neurobiology ... See more keywords