Six3 in a small population of progenitors at E8.5 is required for neuroretinal specification via regulating cell signaling and survival in mice.
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DOI: 10.1016/j.ydbio.2017.05.026
Abstract: Neuroretina and retinal pigment epithelium (RPE) are differentiated from the progenitors in optic vesicles, but it is unclear when and how the two lineages are segregated. Manipulation of chick embryos reveals that the early anteroventral… read more here.
Keywords: neuroretinal specification; population progenitors; small population; required neuroretinal ... See more keywords