Subcutaneous infusion of neurosecretory protein GL promotes fat accumulation in mice
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e07502
Abstract: We recently identified a novel small secretory protein, neurosecretory protein GL (NPGL), in the vertebrate hypothalamus. We revealed that NPGL is involved in energy homeostasis using intracerebroventricular infusion in rodents. However, the effect of NPGL… read more here.
Keywords: infusion; neurosecretory protein; subcutaneous infusion; fat accumulation ... See more keywords
Avian and murine neurosecretory protein GL participates in the regulation of feeding and energy metabolism.
Sign Up to like & getrecommendations! Published in 2018 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2017.09.019
Abstract: Probing previously unknown neuropeptides and/or peptide hormones is essential for our understanding of the regulation of energy homeostasis in the brain. We recently performed a cDNA subtractive screening of the chicken hypothalamus, which contained one… read more here.
Keywords: protein; feeding energy; energy; neurosecretory protein ... See more keywords
Localization and function of neurosecretory protein GM, a novel small secretory protein, in the chicken hypothalamus
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18822-9
Abstract: Recently, we discovered a novel cDNA encoding the precursor of a small secretory protein, neurosecretory protein GL (NPGL), in the hypothalamic infundibulum of chickens. NPGL plays an important role in the regulation of growth and… read more here.
Keywords: protein; small secretory; secretory protein; neurosecretory protein ... See more keywords
Neurosecretory Protein GL, a Hypothalamic Small Secretory Protein, Participates in Energy Homeostasis in Male Mice
Sign Up to like & getrecommendations! Published in 2017 at "Endocrinology"
DOI: 10.1210/en.2017-00064
Abstract: We have recently identified from the avian hypothalamus a complementary DNA encoding a small secretory protein termed neurosecretory protein GL (NPGL). In chicks, NPGL increases body weight gain without affecting food intake. A database search… read more here.
Keywords: protein; small secretory; hypothalamus; energy homeostasis ... See more keywords
Effect of Stressors on the mRNA Expressions of Neurosecretory Protein GL and Neurosecretory Protein GM in Chicks
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.860912
Abstract: We recently discovered novel cDNAs encoding the precursors of two small secretory proteins, neurosecretory protein GL (NPGL) and neurosecretory protein GM (NPGM), in the mediobasal hypothalamus (MBH) of chickens. In addition, we found colocalization of… read more here.
Keywords: effect; hdc; neurosecretory protein; mrna expression ... See more keywords
Immunohistochemical Analysis of Neurotransmitters in Neurosecretory Protein GL-Producing Neurons of the Mouse Hypothalamus
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020454
Abstract: We recently discovered a novel neuropeptide of 80 amino acid residues: neurosecretory protein GL (NPGL), in the hypothalamus of birds and rodents. NPGL is localized in the lateral posterior part of the arcuate nucleus (ArcLP),… read more here.
Keywords: neurosecretory protein; immunohistochemical analysis; npgl neurons; analysis neurotransmitters ... See more keywords
Effects of Irregular Feeding on the Daily Fluctuations in mRNA Expression of the Neurosecretory Protein GL and Neurosecretory Protein GM Genes in the Mouse Hypothalamus
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22042109
Abstract: Circadian desynchrony induced by a long period of irregular feeding leads to metabolic diseases, such as obesity and diabetes mellitus. The recently identified neurosecretory protein GL (NPGL) and neurosecretory protein GM (NPGM) are hypothalamic small… read more here.
Keywords: protein; npgl npgm; irregular feeding; neurosecretory protein ... See more keywords