24 hour patterning in gene expression of pineal neurosteroid biosynthesis in young chickens (Gallus gallus domesticus L.)
Sign Up to like & getrecommendations! Published in 2020 at "Chronobiology International"
DOI: 10.1080/07420528.2020.1823404
Abstract: ABSTRACT The pineal gland, one of the three equivalent avian biological clock structures, is also the site of intensive neurosteroid synthesis (7α-hydroxypregnenolone and allopregnanolone). Pineal neurosteroid biosynthesis involves six enzymes: cytochrome P450 side-chain cleavage –… read more here.
Keywords: neurosteroid biosynthesis; pineal neurosteroid; pineal; gene ... See more keywords
Neurosteroid biosynthesis down‐regulation and changes in GABAA receptor subunit composition: a biomarker axis in stress‐induced cognitive and emotional impairment
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Pharmacology"
DOI: 10.1111/bph.13843
Abstract: By rapidly modulating neuronal excitability, neurosteroids regulate physiological processes, such as responses to stress and development. Excessive stress affects their biosynthesis and causes an imbalance in cognition and emotions. The progesterone derivative, allopregnanolone (Allo) enhances… read more here.
Keywords: gabaa receptor; biosynthesis; neurosteroid biosynthesis; stress induced ... See more keywords