Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107776
Abstract: Glaucoma is a neurodegenerative disease that features the death of retinal ganglion cells (RGCs) in the retina, often as a result of prolonged increases in intraocular pressure. We show that preventing the formation of neuroinflammatory… read more here.
Keywords: reactive astrocytes; death; neurotoxic reactive; injury ... See more keywords
Neurotoxic reactive astrocytes induce cell death via saturated lipids.
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03960-y
Abstract: Astrocytes regulate the response of the central nervous system to disease and injury and have been hypothesized to actively kill neurons in neurodegenerative disease1-6. Here we report an approach to isolate one component of the… read more here.
Keywords: reactive astrocytes; saturated lipids; astrocytes induce; induce cell ... See more keywords