Articles with "neurotoxic soluble" as a keyword



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Neurotoxic Soluble Amyloid Oligomers Drive Alzheimer’s Pathogenesis and Represent a Clinically Validated Target for Slowing Disease Progression

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22126355

Abstract: A large body of clinical and nonclinical evidence supports the role of neurotoxic soluble beta amyloid (amyloid, Aβ) oligomers as upstream pathogenic drivers of Alzheimer’s disease (AD). Recent late-stage trials in AD that have evaluated… read more here.

Keywords: oligomers drive; neurotoxic soluble; disease progression; amyloid oligomers ... See more keywords