Aesculin offers increased resistance against oxidative stress and protective effects against Aβ-induced neurotoxicity in Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2022.174755
Abstract: Aesculin, a coumarin compound, is one of the major active ingredients of traditional Chinese herbal medicine Qinpi (Cortex Fraxini), which has been reported to exhibit antioxidative, anti-inflammatory and neuroprotective properties against oxidative stress and cellular… read more here.
Keywords: stress; resistance; oxidative stress; neurotoxicity caenorhabditis ... See more keywords
Caenorhabditis elegans as a Model to Study Manganese-Induced Neurotoxicity
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101396
Abstract: Caenorhabditis elegans (C. elegans) is a nematode present worldwide. The worm shows homology to mammalian systems and expresses approximately 40% of human disease-related genes. Since Dr. Sydney Brenner first proposed C. elegans as an advantageous… read more here.
Keywords: caenorhabditis elegans; elegans model; neurotoxicity; neurotoxicity caenorhabditis ... See more keywords