Yeast Display Enables Identification of Covalent Single-Domain Antibodies against Botulinum Neurotoxin Light Chain A.
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DOI: 10.1021/acschembio.2c00574
Abstract: While covalent drug discovery is reemerging as an important route to small-molecule therapeutic leads, strategies for the discovery and engineering of protein-based irreversible binding agents remain limited. Here, we describe the use of yeast display… read more here.
Keywords: yeast display; display; single domain; neurotoxin light ... See more keywords