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   Articles with "neurotransmitter" as a keyword



On the difficulties of characterizing weak protein interactions that are critical for neurotransmitter release

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recommendations! Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13473

Abstract: The mechanism of neurotransmitter release has been extensively characterized, showing that vesicle fusion is mediated by the SNARE complex formed by syntaxin‐1, SNAP‐25 and synaptobrevin. This complex is disassembled by N‐ethylmaleimide sensitive factor (NSF) and… read more here.

Keywords: neurotransmitter; weak interactions; neurotransmitter release; protein interactions ... See more keywords

Tonotopic differentiation of presynaptic neurotransmitter‐releasing machinery in the auditory brainstem during the prehearing period and its selective deficits in Fmr1 knockout mice

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recommendations! Published in 2022 at "Journal of Comparative Neurology"

DOI: 10.1002/cne.25406

Abstract: Tonotopic organization is a fundamental feature of the auditory system. In the developing auditory brainstem, the ontogeny and maturation of neurotransmission progress from high to low frequencies along the tonotopic axis. To explore the underlying… read more here.

Keywords: tonotopic differentiation; auditory brainstem; prehearing period; neurotransmitter ... See more keywords
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Neurochemical Organization of the Drosophila Brain Visualized by Endogenously Tagged Neurotransmitter Receptors.

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recommendations! Published in 2020 at "Cell reports"

DOI: 10.1016/j.celrep.2019.12.018

Abstract: Neurotransmitters often have multiple receptors that induce distinct responses in receiving cells. Expression and localization of neurotransmitter receptors in individual neurons are therefore critical for understanding the operation of neural circuits. Here we describe a… read more here.

Keywords: organization drosophila; neurotransmitter; neurochemical organization; neurotransmitter receptors ... See more keywords

Nafion-stabilized two-dimensional transition metal carbide (Ti3C2Tx MXene) as a high-performance electrochemical sensor for neurotransmitter

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recommendations! Published in 2019 at "Journal of Industrial and Engineering Chemistry"

DOI: 10.1016/j.jiec.2019.03.061

Abstract: Abstract Herein, we demonstrate the selective sensing of Dopamine (DA), an important neurotransmitter, by using Nafion-stabilized two-dimensional transition metal carbides (Ti3C2Tx MXenes). Ti3C2Tx was deposited on a glassy carbon electrode followed by Nafion coating to… read more here.

Keywords: transition metal; stabilized two; neurotransmitter; two dimensional ... See more keywords
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Anatomic resolution of neurotransmitter-specific projections to the VTA reveals diversity of GABAergic inputs

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recommendations! Published in 2020 at "Nature Neuroscience"

DOI: 10.1038/s41593-020-0657-z

Abstract: The ventral tegmental area (VTA) is important for reward processing and motivation. The anatomic organization of neurotransmitter-specific inputs to the VTA remains poorly resolved. In the present study, we mapped the major neurotransmitter projections to… read more here.

Keywords: resolution neurotransmitter; anatomic resolution; gabaergic inputs; projections vta ... See more keywords

Chromogranin A and catestatin regulate pancreatic islet homeostasis, endocrine function, and neurotransmitter signaling

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recommendations! Published in 2025 at "Communications Biology"

DOI: 10.1038/s42003-025-09135-z

Abstract: Chromogranin A (CgA), a neuroendocrine pro-hormone, is proteolytically cleaved into bioactive peptides, most notably catestatin (CST) and pancreastatin (PST), which exert opposing effects on metabolic and inflammatory processes. Using CgA- and CST knockout (KO) mice,… read more here.

Keywords: homeostasis; chromogranin; function; endocrine function ... See more keywords

An organic brain-inspired platform with neurotransmitter closed-loop control, actuation and reinforcement learning

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recommendations! Published in 2024 at "Materials Horizons"

DOI: 10.1039/d3mh02202a

Abstract: Organic neuromorphic platforms have recently received growing interest for the implementation and integration of artificial and hybrid neuronal networks. Here, achieving closed-loop and learning/training processes as in the human brain is still a major challenge… read more here.

Keywords: brain; control; neurotransmitter; platform ... See more keywords
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Mechanism for neurotransmitter-receptor matching

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recommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.1916600117

Abstract: Significance Neurotransmitter switching generally involves replacement of an excitatory transmitter with an inhibitory transmitter or vice versa and has been linked to changes in animal behavior. There are corresponding switches in postsynaptic receptors that enable… read more here.

Keywords: mechanism; transmitter; neurotransmitter; expression ... See more keywords

Structure and Gating Dynamics of Na+/Cl– Coupled Neurotransmitter Transporters

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recommendations! Published in 2019 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2019.00080

Abstract: Neurotransmitters released at the neural synapse through vesicle exocytosis are spatiotemporally controlled by the action of neurotransmitter transporters. Integral membrane proteins of the solute carrier 6 (SLC6) family are involved in the sodium and chloride… read more here.

Keywords: neurotransmitter transporters; structure gating; gating dynamics; dynamics coupled ... See more keywords

Neurotransmitter content heterogeneity within an interneuron class shapes inhibitory transmission at a central synapse

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recommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2022.1060189

Abstract: Neurotransmitter content is deemed the most basic defining criterion for neuronal classes, contrasting with the intercellular heterogeneity of many other molecular and functional features. Here we show, in the adult mouse brain, that neurotransmitter content… read more here.

Keywords: heterogeneity; class; content heterogeneity; neurotransmitter content ... See more keywords

Effects of microsurgery on short-term serum neurotransmitter levels and long-term cerebral neurological function in elderly patients with spontaneous intracerebral hemorrhage

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recommendations! Published in 2025 at "Frontiers in Neurology"

DOI: 10.3389/fneur.2025.1653647

Abstract: Objective This study explores the impact of microsurgery on postoperative serum neurotransmitter levels and long-term neurological outcomes in elderly spontaneous intracerebral hemorrhage (SICH) patients. Methods A single-center, prospective, and single-arm cohort study was conducted, enrolling… read more here.

Keywords: term; serum; long term; neurotransmitter ... See more keywords