Articles with "neurotrophic factor" as a keyword



Impact of brain‐derived neurotrophic factor genetic polymorphism on cognition: A systematic review

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Published in 2018 at "Brain and Behavior"

DOI: 10.1002/brb3.1009

Abstract: Brain‐derived neurotrophic factor (BDNF) has an important role in the neurogenesis and neuroplasticity of the brain. This systematic review was designed to examine the association between BDNF Val66Met (rs6265) polymorphism and four cognitive domains—attention and… read more here.

Keywords: brain derived; derived neurotrophic; systematic review; neurotrophic factor ... See more keywords

Association of peripheral manifestation of brain‐derived neurotrophic factor with depression: A meta‐analysis

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Published in 2022 at "Brain and Behavior"

DOI: 10.1002/brb3.2581

Abstract: The relationship between brain‐derived neurotrophic factor (BDNF) and depression is a hot topic in research as several results of preclinical and clinical studies have shown controversial results. Our meta‐analysis aims to evaluate and update the… read more here.

Keywords: meta analysis; derived neurotrophic; brain derived; depression ... See more keywords

Can neurocognition, brain neurotrophic factor, triglyceride, and total cholesterol predict suicidal ideation in first‐episode Han Chinese patients with schizophrenia?

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Published in 2024 at "Brain and Behavior"

DOI: 10.1002/brb3.3499

Abstract: Previous studies have suggested that the suicide rate of patients with schizophrenia is high. This study investigates factors influencing suicidal ideation in first‐episode schizophrenia patients, focusing on cognitive function, brain‐derived neurotrophic factor (BDNF), triglyceride (TG),… read more here.

Keywords: neurotrophic factor; first episode; brain; suicidal ideation ... See more keywords

Association of Brain‐derived Neurotrophic Factor Polymorphisms With Alcohol Use Disorder: An Updated Meta‐Analysis of Genetic Association Studies

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Published in 2025 at "Brain and Behavior"

DOI: 10.1002/brb3.70359

Abstract: Brain‐derived neurotrophic factor (BDNF) has been proposed to play a role in chronic alcohol consumption. However, studies investigating the association of single nucleotide polymorphisms (SNPs) in the BDNF gene with alcohol use disorder (AUD), including… read more here.

Keywords: neurotrophic factor; brain; alcohol; brain derived ... See more keywords

Assessing Causality Between Plasma Brain‐Derived Neurotrophic Factor With Major Depression Disorder: A Bidirectional Mendelian Randomization Study

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Published in 2025 at "Brain and Behavior"

DOI: 10.1002/brb3.70425

Abstract: This study employed a two‐sample Mendelian randomization (MR) approach to investigate the bidirectional relationship between brain‐derived neurotrophic factor (BDNF) and major depressive disorder (MDD), addressing gaps left by prior observational studies. read more here.

Keywords: neurotrophic factor; brain; study; mendelian randomization ... See more keywords

Serum brain‐derived neurotrophic factor in coronary heart disease: Correlation with the T helper (Th)1/Th2 ratio, Th17/regulatory T (Treg) ratio, and major adverse cardiovascular events

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Published in 2022 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24803

Abstract: Brain‐derived neurotrophic factor (BDNF) exerts protective roles against dyslipidemia, atherosclerosis, and inflammation in cardiovascular diseases; meanwhile, it retards CD4+ T cell differentiation into T helper (Th)1 and Th17 cells. Hence, this study aimed to investigate… read more here.

Keywords: derived neurotrophic; th2 ratio; brain derived; th17 ... See more keywords
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Glial-derived neurotrophic factor in human airway smooth muscle.

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Published in 2021 at "Journal of cellular physiology"

DOI: 10.1002/jcp.30489

Abstract: Airway smooth muscle (ASM) cells modulate the local airway milieu via production of inflammatory mediators and growth factors including classical neurotrophins, such as brain-derived neurotrophic factor (BDNF). The glial cell-derived neurotrophic factor (GDNF) family of… read more here.

Keywords: derived neurotrophic; asm; smooth muscle; neurotrophic factor ... See more keywords

Sex differences in brain‐derived neurotrophic factor signaling and functions

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Published in 2017 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.23863

Abstract: Brain‐derived neurotrophic factor (BDNF) is a member of the neurotrophin family that plays a critical role in numerous neuronal activities. Recent studies have indicated that some functions or action mechanisms of BDNF vary in a… read more here.

Keywords: brain derived; derived neurotrophic; signaling functions; sex ... See more keywords

Neuroanatomical distribution and functions of brain‐derived neurotrophic factor in zebrafish (Danio rerio) brain

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Published in 2019 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.24536

Abstract: Brain‐derived neurotrophic factor (BDNF) is an extensively studied protein that is evolutionarily conserved and widely distributed in the brain of vertebrates. It acts via its cognate receptors TrkB and p75NTR and plays a central role… read more here.

Keywords: brain derived; derived neurotrophic; neurotrophic factor; brain ... See more keywords

Select neurotrophins promote oligodendrocyte progenitor cell process outgrowth in the presence of chondroitin sulfate proteoglycans

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Published in 2021 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.24780

Abstract: Axonal damage and the subsequent interruption of intact neuronal pathways in the spinal cord are largely responsible for the loss of motor function after injury. Further exacerbating this loss is the demyelination of neighboring uninjured… read more here.

Keywords: chondroitin sulfate; oligodendrocyte progenitor; sulfate proteoglycans; neurotrophic factor ... See more keywords

The First and Last Time I Met Rita Levi-Montalcini: From the Insect Neurotrophic Factor to the Nerve Growth Factor Clinical Application : RLM and the Discovery of Two Neurotrophic Factors.

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Published in 2021 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-030-74046-7_2

Abstract: The neurotrophic factor nerve growth factor (NGF) has been discovered in the 1950s by Rita Levi-Montalcini, first in a neoplastic tissue and, later, in the mouse salivary gland (see 1A). Levi-Montalcini characterized its action in… read more here.

Keywords: rita levi; nerve growth; growth factor; neurotrophic factor ... See more keywords