In vivo microscopic and optical coherence tomography classification of neurotrophic keratopathy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27345
Abstract: Neurotrophic keratopathy (NK) is a rare degenerative corneal disorder characterized by instability of epithelial integrity with consequent epithelial defects that can worsen up to persistent epithelial defects with stromal melting and ulceration. The pathogenesis of… read more here.
Keywords: optical coherence; classification; neurotrophic keratopathy; coherence tomography ... See more keywords
Neurotrophic keratopathy
Sign Up to like & getrecommendations! Published in 2018 at "Progress in Retinal and Eye Research"
DOI: 10.1016/j.preteyeres.2018.04.003
Abstract: Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to frank epithelial defect with or without stromal ulceration (melting) is associated with reduced or absent corneal sensations. Sensory nerves serve nociceptor and trophic… read more here.
Keywords: neurotrophic keratopathy; corneal; pathology;
Associated Neurotrophic Keratopathy in Complex Regional Pain Syndrome
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DOI: 10.1097/ico.0000000000002684
Abstract: Purpose: To report a case of neurotrophic keratopathy (NK) in a patient with complex regional pain syndrome (CRPS) with ipsilateral facial involvement. Methods: Case report. Results: An 18-year old woman with a 5-year history of… read more here.
Keywords: neurotrophic keratopathy; complex regional; pain; pain syndrome ... See more keywords
Neurotrophic Keratopathy After Herpes Zoster Ophthalmicus
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DOI: 10.1097/ico.0000000000003003
Abstract: Purpose: The aim of this study was to describe risk factors for neurotrophic keratopathy (NK) after herpes zoster ophthalmicus (HZO). Methods: This study was a retrospective review of all patients seen at the Auckland District… read more here.
Keywords: zoster ophthalmicus; neurotrophic keratopathy; keratopathy herpes; herpes zoster ... See more keywords
A Case of Neurotrophic Keratopathy Associated with Nasopharyngeal Carcinoma
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DOI: 10.1159/000485965
Abstract: Purpose: To report a case of neurotrophic keratopathy associated with nasopharyngeal carcinoma. Case Report: A 59-year-old man who had been diagnosed with a nasopharyngeal carcinoma was referred to the authors because of visual disturbance and… read more here.
Keywords: keratopathy associated; neurotrophic keratopathy; nasopharyngeal carcinoma; case ... See more keywords
Topical cenegermin 0.002% for pediatric neurotrophic keratopathy
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Ophthalmology"
DOI: 10.1177/11206721221094783
Abstract: Purpose To evaluate the efficacy and safety of cenegermin 0.002% ophthalmic drops in the management of pediatric neurotrophic keratopathy (NK). Methods Retrospective chart review of children under the age of 18 years diagnosed with NK… read more here.
Keywords: cenegermin; neurotrophic keratopathy; cenegermin 002; therapy ... See more keywords
Neurotrophic Keratopathy in Systemic Diseases: A Case Series on Patients Treated With rh-NGF
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.920688
Abstract: Purpose To evaluate the prevalence, clinical ocular presentation and corneal healing in moderate and severe neurotrophic keratopathy (NK) caused by systemic diseases and treated with rh-NGF. Setting Department of Biomedical and Dental Sciences and Morphofunctional… read more here.
Keywords: systemic diseases; treated ngf; case series; neurotrophic keratopathy ... See more keywords
0.1% RGN-259 (Thymosin ß4) Ophthalmic Solution Promotes Healing and Improves Comfort in Neurotrophic Keratopathy Patients in a Randomized, Placebo-Controlled, Double-Masked Phase III Clinical Trial
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010554
Abstract: We determined the efficacy and safety of 0.1% RGN-259 ophthalmic solution (containing the regenerative protein thymosin ß4) in promoting the healing of persistent epithelial defects in patients with Stages 2 and 3 neurotrophic keratopathy. Complete… read more here.
Keywords: efficacy; rgn 259; neurotrophic keratopathy; ophthalmic solution ... See more keywords
Commentary: Corneal neurotization
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_3104_21
Abstract: Conventional treatment for neurotrophic keratopathy is mainly palliative and aims at promoting corneal epithelial regrowth. Medical management is prescribed in the early stages and comprises preservative‐free lubricants, topical antibiotics, and blood‐derived eye drops, whereas surgical… read more here.
Keywords: ophthalmology; neurotrophic keratopathy; commentary corneal; corneal neurotization ... See more keywords