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Published in 2023 at "Glia"
DOI: 10.1002/glia.24370
Abstract: Neurovascular coupling (NVC) modulates cerebral blood flow to match increased metabolic demand during neuronal excitation. Activation of inhibitory interneurons also increase blood flow, but the basis for NVC caused by interneurons is unclear. While astrocyte… read more here.
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Published in 2017 at "European Journal of Applied Physiology"
DOI: 10.1007/s00421-017-3707-9
Abstract: PurposeModels designed to study neurovascular coupling (NVC) describe a possible cerebral hemisphere dominance dependent on task completed and preference in handedness. We investigated whether passive arm manoeuvre performed with dominant (Dom-Arm) or non-dominant arm (ND-Arm)… read more here.
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Published in 2021 at "Brain imaging and behavior"
DOI: 10.1007/s11682-021-00588-4
Abstract: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a recently identified autoimmune disorder with heterogeneous neurological, psychiatric, and cognitive manifestations. The NMDAR is a key signaling node for neurovascular coupling, the mechanism by which cerebral blood perfusion is… read more here.
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Published in 2017 at "Translational Stroke Research"
DOI: 10.1007/s12975-017-0585-8
Abstract: Impaired cerebral autoregulation and neurovascular coupling (NVC) contribute to delayed cerebral ischemia after subarachnoid hemorrhage (SAH). Retinal vessel analysis (RVA) allows non-invasive assessment of vessel dimension and NVC hereby demonstrating a predictive value in the… read more here.
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Published in 2021 at "Cell calcium"
DOI: 10.1016/j.ceca.2021.102407
Abstract: The just-in time delivery of oxygen and nutrients to active brain regions to support function (functional hyperemia; FH) is mediated by not yet fully understood mechanisms collectively referred to as 'neurovascular coupling' (NVC). In a… read more here.
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Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.05.091
Abstract: SUMMARY The role of astrocytes in neurovascular coupling (NVC) is unclear. Here, we applied a multimodality imaging approach to concomitantly measure synchronized neuronal or astrocytic Ca2+ and hemodynamic changes in the mouse somatosensory cortex at… read more here.
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Published in 2018 at "Developmental Cognitive Neuroscience"
DOI: 10.1016/j.dcn.2018.01.001
Abstract: Highlights • Cerebral hemodynamic response is unable to adapt to exogenous stimulation in IVH preterms.• EEG–NIRS coregistration allows to obtain high temporal and spatial resolution measurements in preterm neonates.• Optical imaging identifies pathological cerebral hemodynamics. read more here.
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Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.107753
Abstract: The retina is known to have a local renin-angiotensin system (RAS) and dysfunction in the RAS is often associated with diseases of the retinal vasculature that cause irreversible vision loss. Regulation of the retinal vasculature… read more here.
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Published in 2017 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2017.01.013
Abstract: Abstract Nitric oxide (•NO)‐dependent pathways and cerebrovascular dysfunction have been shown to contribute to the cognitive decline and neurodegeneration observed in Alzheimer's disease (AD) but whether they represent initial factors or later changes of the… read more here.
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Published in 2021 at "Neuroimage"
DOI: 10.1016/j.neuroimage.2020.117652
Abstract: EEG-correlated fMRI analysis is widely used to detect regional BOLD fluctuations that are synchronized to interictal epileptic discharges, which can provide evidence for localizing the ictal onset zone. However, the typical, asymmetrical and mass-univariate approach… read more here.
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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-66227-y
Abstract: Birth asphyxia constitutes a major global public health burden for millions of infants with a critical need for real time physiological biomarkers. This proof of concept study targets the translational rigor of such biomarkers and… read more here.