The molecular reach of antibodies crucially underpins their viral neutralisation capacity
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-024-54916-5
Abstract: Key functions of antibodies, such as viral neutralisation, depend on high-affinity binding. However, viral neutralisation poorly correlates with antigen affinity for reasons that have been unclear. Here, we use a new mechanistic model of bivalent… read more here.
Keywords: viral neutralisation; molecular reach; neutralisation; reach antibodies ... See more keywords
Reduced humoral response 3 months following BNT162b2 vaccination in SARS-CoV-2 uninfected residents of long-term care facilities
Sign Up to like & getrecommendations! Published in 2022 at "Age and Ageing"
DOI: 10.1093/ageing/afac101
Abstract: Abstract Background SARS-CoV-2 vaccination is the most effective strategy to protect older residents of long-term care facilities (LTCF) against severe COVID-19, but primary vaccine responses are less effective in older adults. Here, we characterised the… read more here.
Keywords: long term; older adults; vaccination; neutralisation ... See more keywords
Neutralisation of electrically-charged insulating granular materials
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on Dielectrics and Electrical Insulation"
DOI: 10.1109/tdei.2017.006602
Abstract: During certain electrostatic process, diverse insulating granular materials acquire large amounts of charge, and retain it longer than necessary. The aim of this work was to model and optimize the elimination of the residual static… read more here.
Keywords: neutralisation electrically; granular materials; charged insulating; insulating granular ... See more keywords
Neutralisation of virulence activity of enterohemorrhagic Escherichia coliO157:H7in vitro through hyperimmune bovine colostrum
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Dairy Technology"
DOI: 10.1111/1471-0307.70045
Abstract: Background, Context or RationaleEnterohemorrhagic Escherichia coli (EHEC) O157:H7 infection in humans may cause bloody diarrhoea, haemorrhagic colitis and haemolytic uremic syndrome (HUS). Cattle are the main reservoir of EHEC and a source of infection for… read more here.
Keywords: colostrum; neutralisation; virulence; ehec o157 ... See more keywords
Neutralisation of circulating SARS-CoV-2 delta and omicron variants by convalescent plasma and SARS-CoV-2 hyperimmune intravenous human immunoglobulins for treatment of COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2022-222115
Abstract: Monoclonal antibodies (MAbs), convalescent plasma (CP) and hyperimmune intravenous immunoglobulins are routinely used to treat COVID19 patients with autoimmune disorders, organ transplant patients and patients on immunosuppressive drugs. The recent emergence of rapidly spreading SARSCoV2… read more here.
Keywords: omicron; neutralisation; sarscov2; neutralisation titres ... See more keywords
Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccination
Sign Up to like & getrecommendations! Published in 2022 at "RMD Open"
DOI: 10.1136/rmdopen-2022-002639
Abstract: Objective The level of neutralising capacity against Omicron BA.1 and BA.2 after third COVID-19 vaccination in patients on paused or continuous methotrexate (MTX) therapy is unclear. Methods In this observational cohort study, neutralising serum activity… read more here.
Keywords: booster vaccination; vaccination; neutralisation; methotrexate ... See more keywords
‘They would rather not have known and me kept my mouth shut’: The role of neutralisation in responding to the disclosure of childhood sexual abuse
Sign Up to like & getrecommendations! Published in 2022 at "Qualitative Social Work"
DOI: 10.1177/14733250221124300
Abstract: There is a well-established literature examining how perpetrators of child sexual abuse (CSA) neutralise the norms and beliefs that ordinarily prohibit such behaviours. However, there has been substantially less focus on how such techniques of… read more here.
Keywords: neutralisation; sexual abuse; abuse; childhood sexual ... See more keywords
Neutralisation of the SARS-CoV-2 Delta variant sub-lineages AY.4.2 and B.1.617.2 with the mutation E484K by Comirnaty (BNT162b2 mRNA) vaccine-elicited sera, Denmark, 1 to 26 November 2021
Sign Up to like & getrecommendations! Published in 2021 at "Eurosurveillance"
DOI: 10.2807/1560-7917.es.2021.26.49.2101059
Abstract: Several factors may account for the recent increased spread of the SARS-CoV-2 Delta sub-lineage AY.4.2 in the United Kingdom, Romania, Poland, and Denmark. We evaluated the sensitivity of AY.4.2 to neutralisation by sera from 30… read more here.
Keywords: bnt162b2 mrna; comirnaty bnt162b2; neutralisation; mrna vaccine ... See more keywords
SARS-CoV-2 Omicron variant BA.2 neutralisation in sera of people with Comirnaty or CoronaVac vaccination, infection or breakthrough infection, Hong Kong, 2020 to 2022
Sign Up to like & getrecommendations! Published in 2022 at "Eurosurveillance"
DOI: 10.2807/1560-7917.es.2022.27.18.2200178
Abstract: Background Omicron subvariant BA.2 circulation is rapidly increasing globally. Aim We evaluated the neutralising antibody response from vaccination or prior SARS-CoV-2 infection against symptomatic infection by BA.2 or other variants. Methods Using 50% plaque reduction… read more here.
Keywords: comirnaty coronavac; vaccination; infection; neutralisation ... See more keywords
Post-Neutralisation Activated Clotting Time and Postoperative Transfusions in Cardiac Surgery Outcome.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the College of Physicians and Surgeons--Pakistan : JCPSP"
DOI: 10.29271/jcpsp.2024.11.1533
Abstract: OBJECTIVE To assess the impact of post-protamine neutralisation activated clotting time (ACT) values on postoperative outcomes including chest drain output, transfusion requirements, and CICU stay, in patients undergoing cardiac surgery. STUDY DESIGN Observational comparative study.… read more here.
Keywords: neutralisation; clotting time; activated clotting; post ... See more keywords
Complement-Mediated Neutralisation Identified in Ebola Virus Disease Survivor Plasma: Implications for Protection and Pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.857481
Abstract: The 2013–2016 Ebola virus (EBOV) epidemic in West Africa was unprecedented in case numbers and fatalities, and sporadic outbreaks continue to arise. Antibodies to the EBOV glycoprotein (GP) are strongly associated with survival and their… read more here.
Keywords: protection; complement; neutralisation; plasma ... See more keywords