Neutralization sensitivity of genital tract HIV-1: shift in selective milieu shapes the population available to transmit.
Sign Up to like & getrecommendations! Published in 2021 at "AIDS"
DOI: 10.1097/qad.0000000000002912
Abstract: OBJECTIVE Previous studies indicate that transmitted/founder HIV-1 isolates are sensitive to neutralization by the transmitting donor's antibodies. This is true in at least a subset of sexual transmissions. We investigated whether this selection for neutralization-sensitive… read more here.
Keywords: hiv; neutralization; genital tract; neutralization sensitivity ... See more keywords
Neutralization Sensitivity and Evolution of Virus in a Chronic HIV-1 Clade B Infected Patient with Neutralizing Activity against Membrane-Proximal External Region
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DOI: 10.3390/pathogens12030497
Abstract: The membrane-proximal external region (MPER) is a promising HIV-1 vaccine target owing to its linear neutralizing epitopes and highly conserved amino acids. Here, we explored the neutralization sensitivity and investigated the MPER sequences in a… read more here.
Keywords: hiv; neutralization sensitivity; sensitivity; external region ... See more keywords