Epitope competition and neutralizing antidrug antibodies: immune monitoring of antiprogrammed deathâ1 therapies and lessons learned from natalizumab
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Dermatology"
DOI: 10.1111/bjd.19137
Abstract: We read with interest the BJD online publication by Gambichler and colleagues1 about a decline of programmed death (PD)-1+ circulating T regulatory cells (Tregs) predicting clinical outcome in anti-PD-1 therapy. The study highlights the potential… read more here.
Keywords: death; immune monitoring; neutralizing antidrug; competition neutralizing ... See more keywords
Neutralizing antidrug antibody to emicizumab in a patient with severe hemophilia A with inhibitors: New case with detailed laboratory evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14957
Abstract: Hemophilia A is an inherited bleeding disorder characterized by deficiency of the coagulation protein factor VIII. Development of clotting factor concentrates has resulted in an excellent prognosis for this historically fatal disease. However, neutralizing antidrug… read more here.
Keywords: severe hemophilia; neutralizing antidrug; antibody; patient severe ... See more keywords