The impact of neutralizing monoclonal antibodies on the outcomes of COVID‐19 outpatients: A systematic review and meta‐analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27623
Abstract: To assess the clinical efficacy and safety of neutralizing monoclonal antibodies (mABs) for outpatients with coronavirus disease 2019 (COVID‐19). PubMed, Embase, Web of Science, Cochrane Library, ClinicalTrials.gov, and World Health Organization International Clinical Trials Registry… read more here.
Keywords: risk; covid outpatients; neutralizing monoclonal; patients received ... See more keywords
Novel neutralizing monoclonal antibodies against Junin virus
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DOI: 10.1016/j.antiviral.2018.06.002
Abstract: ABSTRACT Junin virus (JUNV) is the pathogen of Argentine haemorrhagic fever which results in high lethality, while there is limited therapeutics available. Here, a series of mouse monoclonal antibodies (mAbs) were isolated through immunization with… read more here.
Keywords: novel neutralizing; monoclonal antibodies; antibodies junin; neutralizing monoclonal ... See more keywords
Neutralizing monoclonal antibodies for COVID-19 treatment and prevention
Sign Up to like & getrecommendations! Published in 2020 at "Biomedical Journal"
DOI: 10.1016/j.bj.2020.11.011
Abstract: The SARS-CoV-2 pandemic has caused unprecedented global health and economic crises. Several vaccine approaches and repurposed drugs are currently under evaluation for safety and efficacy. However, none of them have been approved for COVID-19 yet.… read more here.
Keywords: nmabs targeting; monoclonal antibodies; treatment; neutralizing monoclonal ... See more keywords
Neutralizing monoclonal antibodies against highly pathogenic coronaviruses
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DOI: 10.1016/j.coviro.2021.12.015
Abstract: The pandemic of Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 coronavirus (SARS-CoV-2) is a continuing worldwide threat to human health and social economy. Historically, SARS-CoV-2 follows SARS and MERS as the… read more here.
Keywords: sars cov; neutralizing monoclonal; antibodies highly; monoclonal antibodies ... See more keywords
Neutralizing Monoclonal Antibodies for Coronavirus Disease 2019 (COVID-19) in Pregnancy
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DOI: 10.1097/aog.0000000000004689
Abstract: Treatment with neutralizing monoclonal antibodies for coronavirus disease-2019 (COVID-19) is generally well tolerated in pregnancy. read more here.
Keywords: coronavirus disease; neutralizing monoclonal; antibodies coronavirus; disease 2019 ... See more keywords
Neutralizing monoclonal antibodies in haematological patients paucisymptomatic for COVID‐19: The GIMEMA EMATO‐0321 study
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18385
Abstract: COVID‐19 continues to be a relevant issue among patients with haematological malignancies (HM). Vaccines are frequently not effective in subjects on active treatment. In this multicentre retrospective study of Gruppo Italiano Malattie EMatologiche dell'Adulto (GIMEMA),… read more here.
Keywords: antibodies haematological; neutralizing monoclonal; haematological patients; gimema ... See more keywords
Neutralizing Monoclonal Antibodies to Fight HIV-1: On the Threshold of Success
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DOI: 10.3389/fimmu.2016.00661
Abstract: Anti-human immunodeficiency virus type-1 (anti-HIV-1) neutralizing monoclonal antibodies are broadening the spectrum of pre- and post-exposure treatment against HIV-1. A better understanding of how these antibodies develop and interact with particular regions of the viral… read more here.
Keywords: antibodies fight; threshold success; monoclonal antibodies; hiv threshold ... See more keywords
Potent Molecular Feature-based Neutralizing Monoclonal Antibodies as Promising Therapeutics Against SARS-CoV-2 Infection
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.670815
Abstract: The 2019–2020 winter was marked by the emergence of a new coronavirus (SARS-CoV-2) related disease (COVID-19), which started in Wuhan, China. Its high human-to-human transmission ability led to a worldwide spread within few weeks and… read more here.
Keywords: promising therapeutics; monoclonal antibodies; molecular feature; neutralizing monoclonal ... See more keywords
Experience of Rwanda on COVID-19 Case Management: From Uncertainties to the Era of Neutralizing Monoclonal Antibodies
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DOI: 10.3390/ijerph19031023
Abstract: The management of COVID-19 in Rwanda has been dynamic, and the use of COVID-19 therapeutics has gradually been updated based on scientific discoveries. The treatment for COVID-19 remained patient-centered and entirely state-sponsored during the first… read more here.
Keywords: rwanda; neutralizing monoclonal; covid; monoclonal antibodies ... See more keywords
Characterization of a Broadly Neutralizing Monoclonal Antibody against SARS-CoV-2 Variants
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DOI: 10.3390/v14020230
Abstract: The constant mutation of SARS-CoV-2 has led to the emergence of new variants, which call for urgent effective therapeutic interventions. The trimeric spike (S) protein of SARS-CoV-2 is highly immunogenic with the receptor-binding domain (RBD)… read more here.
Keywords: cov variants; monoclonal antibody; broadly neutralizing; neutralizing monoclonal ... See more keywords