Late‐onset and long‐lasting neutropenias in the young: A new entity anticipating immune‐dysregulation disorders
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DOI: 10.1002/ajh.27221
Abstract: This study identifies a new chronic form of immune neutropenia in the young with or without detectable indirect anti‐neutrophil antibodies, characterized by mild/moderate neutropenia low risk of severe infection (14%), tendency to develop autoimmune phenomena… read more here.
Keywords: neutropenias young; long lasting; late onset; onset long ... See more keywords
Development of a predictive model for neutropenia risk in Japanese breast cancer patients treated with doxorubicin and cyclophosphamide.
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DOI: 10.1002/bcp.70259
Abstract: Chemotherapy‐induced neutropenia (CIN) and febrile neutropenia (FN) are important considerations for anticancer drug dosing. Recent studies suggest that CIN may also improve survival. This study aimed to assess the impact of CIN on survival outcomes… read more here.
Keywords: breast cancer; cancer patients; predictive model; neutropenia ... See more keywords
Efficacy and safety of two pegfilgrastim biosimilars: Tripegfilgrastim and pegteograstim
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DOI: 10.1002/cam4.3261
Abstract: Our aim was to compare the efficacy and safety of two recently developed biosimilars of pegfilgrastim, a pegylated form of the recombinant human granulocyte‐colony stimulating factor (G‐CSF) analog filgrastim with those of the reference pegfilgrastim.… read more here.
Keywords: efficacy safety; safety; reference; pegfilgrastim ... See more keywords
Hematologic safety of palbociclib in combination with endocrine therapy in patients with benign ethnic neutropenia and advanced breast cancer
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DOI: 10.1002/cncr.33620
Abstract: Cyclin‐dependent kinase 4/6 (CDK4/6) inhibitors, including palbociclib, are approved to treat hormone receptor (HR)‐positive/human epidermal growth factor receptor 2 (HER2)‐negative advanced breast cancer (ABC) and are associated with hematologic toxicity. African American women, who are… read more here.
Keywords: ethnic neutropenia; advanced breast; breast cancer; cancer ... See more keywords
Prolonged severe neutropenia after the first daratumumab administration for multiple myeloma with baseline neutropenia
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DOI: 10.1007/s00277-019-03711-0
Abstract: Dear Editor, Daratumumab, an anti-CD38 monoclonal antibody, shows substantial efficacy for relapsed and refractory multiple myeloma (MM). Daratumumab also has a clinically manageable and acceptable safety profile. Grade 3–4 neutropenia was recorded in 5–12% of… read more here.
Keywords: treatment; severe neutropenia; therapy; neutropenia ... See more keywords
Altered Monocyte Subsets in Patients with Chronic Idiopathic Neutropenia
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DOI: 10.1007/s10875-019-00694-5
Abstract: To the editor, Chronic idiopathic neutropenia (CIN) of adults is a neutrophil disorder characterized by the persistent and unexplained reduction in the number of peripheral blood (PB) neutrophils below the lower limit of the normal… read more here.
Keywords: cin; cd16; cd14 cd16; chronic idiopathic ... See more keywords
Ecthyma gangrenosum in an infant with neutropenia
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DOI: 10.1007/s12185-020-03037-y
Abstract: A previously healthy 1-year-old girl presented with fever and two skin lesions on her right arm. Five days prior to admission, she had fever and small papules that developed into a necrotic ulcer on her… read more here.
Keywords: skin lesions; gangrenosum infant; infant neutropenia; ecthyma gangrenosum ... See more keywords
Benign ethnic neutropenia.
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DOI: 10.1016/j.blre.2019.06.003
Abstract: Benign ethnic neutropenia (BEN) is one of the most common causes of chronic neutropenia seen in individuals of African, Middle Eastern and West Indian descent, affecting many individuals worldwide. Despite its prevalence, many physicians are… read more here.
Keywords: ethnic neutropenia; ben; condition; benign ethnic ... See more keywords
Protocolo terapéutico de la neutropenia
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DOI: 10.1016/j.med.2020.11.008
Abstract: Resumen Los neutrofilos son un tipo de leucocitos responsables de la defensa antibacteriana y antifungica. Se define neutropenia como el descenso de la cifra normal de neutrofilos y, aunque por si misma no genera sintomas,… read more here.
Keywords: medicine; terap utico; utico neutropenia; protocolo terap ... See more keywords
Neutropenia in Incarcerated Adolescents Secondary to Intranasal Quetiapine Misuse.
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DOI: 10.1089/cap.2020.0118
Abstract: Objective: Between April 2015 and May 2016, a number of young males incarcerated at a Youth Justice center in New South Wales, Australia, were noted to have unexplained and significant neutropenia. None of the adolescents… read more here.
Keywords: quetiapine misuse; center; quetiapine; young people ... See more keywords
Comparative analysis of neutropenia in patients receiving prolonged treatment with ceftaroline
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DOI: 10.1093/jac/dkx452
Abstract: Objectives Ceftaroline is often used in durations greater than that studied in clinical trials. Several retrospective, non-comparative studies have suggested a higher than anticipated incidence of neutropenia in patients receiving prolonged treatment with ceftaroline. We… read more here.
Keywords: treatment; patients receiving; ceftaroline; treatment ceftaroline ... See more keywords