Implantation associated divergence in neutrophil glucocorticoid and cysteine-X-cysteine receptor genes in cattle
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-04865-w
Abstract: The differential roles of Interferon-tau (IFNT) and Progesterone (P4) in triggering pro- and anti-inflammatory responses during peri-implantation period were assessed in cows. An ex vivo study was done by isolating neutrophils from the animals post… read more here.
Keywords: associated divergence; cysteine; neutrophil; receptor ... See more keywords
IFN-λ suppresses intestinal inflammation by non-translational regulation of neutrophil function
Sign Up to like & getrecommendations! Published in 2017 at "Nature Immunology"
DOI: 10.1038/ni.3821
Abstract: Interferon-λ (IFN-λ) is a central regulator of mucosal immunity; however, its signaling specificity relative to that of type I interferons is poorly defined. IFN-λ can induce antiviral interferon-stimulated genes (ISGs) in epithelia, while the effect… read more here.
Keywords: suppresses intestinal; non translational; intestinal inflammation; neutrophil ... See more keywords
Cerebral Concussion Primes the Lungs for Subsequent Neutrophil-Mediated Injury
Sign Up to like & getrecommendations! Published in 2018 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000003270
Abstract: Objectives: Mild traumatic brain injury in the form of concussion is extremely common, and the potential effects on pulmonary priming have been underestimated. The aim of this study was to characterize the pulmonary response following… read more here.
Keywords: traumatic brain; neutrophil; concussion; brain injury ... See more keywords
Progress in Model Systems of Cystic Fibrosis Mucosal Inflammation to Understand Aberrant Neutrophil Activity
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00595
Abstract: In response to recurrent infection in cystic fibrosis (CF), powerful innate immune signals trigger polymorphonuclear neutrophil recruitment into the airway lumen. Exaggerated neutrophil proteolytic activity results in sustained inflammation and scarring of the airways. Consequently,… read more here.
Keywords: cystic fibrosis; aberrant neutrophil; neutrophil; neutrophil activity ... See more keywords
COVID-19 Pathology Sheds Further Light on Balance between Neutrophil Proteases and Their Inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom13010082
Abstract: Excessive neutrophil influx and activation in lungs during infections, such as manifest during the ongoing SARS CoV-2 pandemic, have brought neutrophil extracellular traps (NETs) and the concomitant release of granule contents that damage surrounding tissues… read more here.
Keywords: neutrophil; sheds light; pathology sheds; pathology ... See more keywords
Elevated Baseline Neutrophil Count Correlates with Worse Outcomes in Patients with Muscle-Invasive Bladder Cancer Treated with Chemoradiation
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DOI: 10.3390/cancers15061886
Abstract: Simple Summary Inflammation plays a role in the development and prognosis of bladder cancer. We aimed at studying the prognostic significance of neutrophil-to-lymphocyte ratio (NLR) and neutrophil count (PNN) at baseline in patients with localized… read more here.
Keywords: bladder; neutrophil; pnn; bladder cancer ... See more keywords
Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.72071
Abstract: Infection is a major co-morbidity that contributes to impaired healing in diabetic wounds. Although impairments in diabetic neutrophils have been blamed for this co-morbidity, what causes these impairments and whether they can be overcome, remain… read more here.
Keywords: neutrophil; infection; fpr; diabetic wound ... See more keywords