Decreased ALKBH5 in neutrophil correlates with disease activity in rheumatoid arthritis and ALKBH5 modulates neutrophil autophagy
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-21727-7
Abstract: Neutrophils are key immune components in rheumatoid arthritis (RA), but the role of ALKBH5 in neutrophil function and RA progression remains unclear. METTL3, METTL14, WTAP, ALKBH5, FTO, YTHDF2, autophagy related gene were investigated by RT-qPCR.… read more here.
Keywords: disease activity; alkbh5; rheumatoid arthritis; neutrophil autophagy ... See more keywords
Down-regulation of SHP2 promotes neutrophil autophagy and inhibits neutrophil extracellular trap formation to alleviate asthma through the ERK5 pathway
Sign Up to like & getrecommendations! Published in 2024 at "Central-European Journal of Immunology"
DOI: 10.5114/ceji.2024.143691
Abstract: Introduction Neutrophil autophagy and neutrophil extracellular trap (NET) formation are closely related to asthma pathogenesis. Src homology domain 2-containing protein tyrosine phosphatase 2 (SHP2) is an important regulatory factor in airway remodeling in asthma. This… read more here.
Keywords: neutrophil extracellular; neutrophil like; neutrophil autophagy; shp2 ... See more keywords