Iron regulatory protein (IRP)–mediated iron homeostasis is critical for neutrophil development and differentiation in the bone marrow
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1101/2022.03.16.483971
Abstract: Iron is mostly devoted to the hemoglobinization of erythrocytes for oxygen transport. Yet, emerging evidence points to a broader role for the metal in hematopoiesis, including the formation of the immune system. Iron availability in… read more here.
Keywords: development differentiation; iron; neutrophil development; iron regulatory ... See more keywords
Osteocytes regulate neutrophil development through IL-19: A potent cytokine for neutropenia treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Blood"
DOI: 10.1182/blood.2020007731
Abstract: Osteocytes are the most abundant (90-95%) cells in bone and have emerged as an important regulator of hematopoiesis, but their role in neutrophil development and the underlying mechanisms remain unclear. Interleukin (IL)-19 produced predominantly by… read more here.
Keywords: development potent; potent cytokine; neutropenia treatment; neutrophil development ... See more keywords