T5 Complement protein c5a induces prolonged neutrophil dysfunction in a clinically relevant model of human bacteraemia
Sign Up to like & getrecommendations! Published in 2017 at "Thorax"
DOI: 10.1136/thoraxjnl-2017-210983.5
Abstract: Introduction Critically ill patients are highly susceptible to nosocomial infections including ventilator-associated pneumonia. Susceptibility to nosocomial infection is heavily influenced by immune-cell failure; however the mechanisms underpinning this process remain incompletely understood.1 Previously, we have… read more here.
Keywords: phagocytosis; clinically relevant; blood; c5a ... See more keywords
Neutrophil Dysfunction in the Pathogenesis of Cystic Fibrosis.
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DOI: 10.1182/blood.2021014699
Abstract: Polymorphonuclear neutrophils (PMN) figure prominently in host defense against infection and in non-infectious inflammation. Mobilized early in an inflammatory response, PMN mediate immediate cellular defense against microbes and orchestrate events that culminate in cessation of… read more here.
Keywords: inflammation; dysfunction pathogenesis; neutrophil dysfunction; defense ... See more keywords