Liraglutide enhances the effect of checkpoint blockade through the inhibition of neutrophil extracellular traps in murine lung and liver cancers.
Sign Up to like & getrecommendations! Published in 2022 at "FEBS open bio"
DOI: 10.1002/2211-5463.13499
Abstract: Glucagon-like peptide-1 (GLP-1) regulates glycemic excursions by augmenting insulin production and inhibiting glucagon secretion. Liraglutide, a long-acting GLP-1 analog, can improve glycemic control for treating type 2 diabetes and prevent neutrophil extravasation in inflammation. Here,… read more here.
Keywords: inhibition; lung liver; liver cancers; murine lung ... See more keywords
Elevated neutrophil extracellular traps by HBV‐mediated S100A9‐TLR4/RAGE‐ROS cascade facilitate the growth and metastasis of hepatocellular carcinoma
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DOI: 10.1002/cac2.12388
Abstract: Neutrophil extracellular traps (NETs) are considered significant contributors to cancer progression, especially metastasis. However, it is still unclear whether NETs are involved in hepatitis B virus (HBV)‐related hepatocarcinogenesis and have potential clinical significance during evaluation… read more here.
Keywords: hepatocellular carcinoma; extracellular traps; elevated neutrophil; neutrophil extracellular ... See more keywords
Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250010
Abstract: Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID‐19) pandemic. Neutrophils play a vital role in the immunopathology of… read more here.
Keywords: activation; traps nets; extracellular traps; neutrophil extracellular ... See more keywords
Generation of neutrophil extracellular traps in patients with acute liver failure is associated with poor outcome.
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DOI: 10.1002/hep.32174
Abstract: BACKGROUND AND AIMS Acute liver failure (ALF) is characterized by significant changes in the hemostatic system and by systemic inflammation. The formation of neutrophil extracellular traps (NETs), in which an activated neutrophil expels its DNA,… read more here.
Keywords: neutrophil extracellular; liver failure; dna; acute liver ... See more keywords
Evaluation of neutrophil extracellular traps as the circulating marker for patients with acute coronary syndrome and acute ischemic stroke
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DOI: 10.1002/jcla.23190
Abstract: Neutrophil extracellular traps (NETs) are known to be induced by various factors. In this study, we tried to identify circulating levels of NETs in patients with acute coronary syndrome (ACS) and acute ischemic stroke (AIS)… read more here.
Keywords: neutrophil extracellular; patients acute; acute ischemic; acute coronary ... See more keywords
Neutrophil extracellular traps are associated with enhanced procoagulant activity in liver cirrhosis patients with portal vein thrombosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24433
Abstract: Patients with liver cirrhosis (LC) commonly exhibit hypercoagulability and tend to develop thrombosis. Neutrophil extracellular traps (NETs) are associated with a variety of thrombotic conditions, but their possible value in portal vein thrombosis (PVT) is… read more here.
Keywords: liver cirrhosis; vein thrombosis; extracellular traps; neutrophil extracellular ... See more keywords
Regulation of immune cell signaling by activated protein C
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DOI: 10.1002/jlb.3mir0817-338r
Abstract: Innate immune cells are an essential part of the host defense response, promoting inflammation through release of proinflammatory cytokines or formation of neutrophil extracellular traps. While these processes are important for defense against infectious agents… read more here.
Keywords: immune; neutrophil extracellular; activated protein; regulation immune ... See more keywords
JAGN1 is required for fungal killing in neutrophil extracellular traps: Implications for severe congenital neutropenia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4a0118-030rr
Abstract: Mutations in the gene JAGN1 were recently discovered in patients with severe congenital neutropenia (SCN). Neutrophils release neutrophil extracellular traps (NETs) consisting of decondensed chromatin decorated with various granular proteins such as neutrophil elastase and… read more here.
Keywords: neutrophil extracellular; jagn1; congenital neutropenia; jagn1 required ... See more keywords
Persistence of neutrophil extracellular traps and anticardiolipin auto‐antibodies in post‐acute phase COVID‐19 patients
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DOI: 10.1002/jmv.28209
Abstract: In the early phase of the pandemic, we were among the first to postulate that neutrophil extracellular traps (NETs) play a key role in COVID‐19 pathogenesis. This exploratory prospective study based on 279 individuals showed… read more here.
Keywords: persistence; covid patients; extracellular traps; neutrophil extracellular ... See more keywords
MUC5B induces in vitro neutrophil extracellular trap formation: Implication in otitis media
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DOI: 10.1002/lio2.396
Abstract: Chronic otitis media (COM) is characterized by middle ear fluid predominantly containing cytokines, Nontypeable haemophilus influenzae (NTHi), the mucin MUC5B, and neutrophil extracellular traps (NETs). NETs consist of extracellular DNA coated with antibacterial proteins such… read more here.
Keywords: muc5b induces; neutrophil extracellular; otitis media; extracellular trap ... See more keywords
Imaging of Neutrophils and Neutrophil Extracellular Traps (NETs) with Intravital (In Vivo) Microscopy.
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DOI: 10.1007/978-1-0716-0154-9_26
Abstract: As we have learned during recent years, neutrophils are not just simple foot soldiers of the innate immune system with a restricted set of pro-inflammatory functions, and instead, they perform sophisticated functions (some of them… read more here.
Keywords: neutrophil extracellular; microscopy; imaging neutrophils; neutrophils neutrophil ... See more keywords