Neutrophil granulocytes promote flow stagnation due to dynamic capillary stalls following experimental stroke
Sign Up to like & getrecommendations! Published in 2021 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2021.01.011
Abstract: Flow stagnation of peri-ischemic capillaries due to dynamic leukocyte stalls has been described to be a contributor to ongoing penumbral injury in transient brain ischemia, but has not been investigated in permanent experimental stroke so… read more here.
Keywords: capillary stalls; neutrophil granulocytes; experimental stroke; due dynamic ... See more keywords
Phagocyte function of peripheral neutrophil granulocytes and monocytes in endometriosis before and after surgery.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of gynecology obstetrics and human reproduction"
DOI: 10.1016/j.jogoh.2020.101796
Abstract: INTRODUCTION Endometriosis is a chronic systemic disease, which influence negatively the quality of life of affected women and responsible for infertility and chronic pelvic pain. Pathophysiology of the disease is still enigmatic, but insufficient immune… read more here.
Keywords: function peripheral; women endometriosis; peripheral neutrophil; neutrophil granulocytes ... See more keywords
Effect of salivary agglutination on oral streptococcal clearance by human polymorphonuclear neutrophil granulocytes
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Oral Microbiology"
DOI: 10.1111/omi.12164
Abstract: Salivary agglutination is an important host defense mechanism to aggregate oral commensal bacteria as well as invading pathogens. Saliva flow and subsequent swallowing more easily clear aggregated bacteria compared with single cells. Phagocytic clearance of… read more here.
Keywords: neutrophil granulocytes; effect salivary; polymorphonuclear neutrophil; clearance ... See more keywords
Next Generation Proteomics of Human Neutrophil Granulocytes in Monogenic Disease
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-114764
Abstract: Background and objective Neutrophil granulocytes (NG) are critical mediators of innate immunity and tissue regeneration. Few monogenic diseases affecting their differentiation and/or function have been described, yet a systems-biology perspective has not yet been opened.… read more here.
Keywords: neutrophil granulocytes; analysis; disease; expression ... See more keywords
Human genetic defects in SRP19 and SRPRA cause severe congenital neutropenia with distinctive proteome changes.
Sign Up to like & getrecommendations! Published in 2022 at "Blood"
DOI: 10.1182/blood.2022016783
Abstract: The mechanisms of coordinated changes in proteome composition and their relevance for the differentiation of neutrophil granulocytes are not well studied. Here, we discover two novel human genetic defects in SRPRA and SRP19, constituents of… read more here.
Keywords: defects srp19; human genetic; genetic defects; neutrophil granulocytes ... See more keywords
Behavior of Neutrophil Granulocytes during Toxoplasma gondii Infection in the Central Nervous System
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2017.00259
Abstract: Cerebral toxoplasmosis is characterized by activation of brain resident cells and recruitment of specific immune cell subsets from the periphery to the central nervous system (CNS). Our studies revealed that the rapidly invaded Ly6G+ neutrophil… read more here.
Keywords: neutrophil granulocytes; nervous system; central nervous; ly6g ... See more keywords
Therapeutic Targeting of Neutrophil Granulocytes in Inflammatory Liver Disease
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02257
Abstract: Neutrophil granulocytes are the most numerous type of leukocyte in humans bearing an enormous, yet largely unexplored therapeutic potential. Scientists have very recently increased their efforts to study and understand these cells which contribute to… read more here.
Keywords: neutrophil granulocytes; therapeutic targeting; targeting neutrophil; activation ... See more keywords
Inhibition of Arginase 1 Liberates Potent T Cell Immunostimulatory Activity of Human Neutrophil Granulocytes
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.617699
Abstract: Myeloid cell arginase-mediated arginine depletion with consecutive inhibition of T cell functions is a key component of tumor immune escape. Both, granulocytic myeloid-derived suppressor cells (G-MDSC) and conventional mature human polymorphonuclear neutrophil granulocytes (PMN) express… read more here.
Keywords: neutrophil granulocytes; arginase; inhibition; cell ... See more keywords
The Impact of TRAIL on the Immunological Milieu during the Early Stage of Abdominal Sepsis
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15061773
Abstract: Simple Summary Sepsis is the leading cause of morbidity and mortality worldwide. It reflects a deficiency in the interplay between the innate and adaptive immune response and leads to an injury of the body’s own… read more here.
Keywords: sepsis; trail; apoptosis; abdominal sepsis ... See more keywords
The Low Expression of Fc-Gamma Receptor III (CD16) and High Expression of Fc-Gamma Receptor I (CD64) on Neutrophil Granulocytes Mark Severe COVID-19 Pneumonia
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12082010
Abstract: Hyperinflammation through neutrophil granulocytes contributes to disease severity in COVID-19 pneumonia and promotes acute lung failure. Understanding the mechanisms of the dysregulations within the myeloid cell compartment may help to improve therapies for severe COVID-19… read more here.
Keywords: gamma receptor; receptor; expression gamma; neutrophil granulocytes ... See more keywords