Neutrophil infiltration is a favorable prognostic factor in early stages of colon cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Human pathology"
DOI: 10.1016/j.humpath.2017.08.028
Abstract: The tumor immune response has been proven critical to prognosis in colorectal cancer (CRC), but studies on the prognostic role of neutrophil infiltration have shown contradictory results. The aim of this study was to elucidate… read more here.
Keywords: neutrophil infiltration; infiltration; prognostic factor; colon ... See more keywords
Augmented early aged neutrophil infiltration contributes to late remodeling post myocardial infarction.
Sign Up to like & getrecommendations! Published in 2021 at "Microvascular research"
DOI: 10.1016/j.mvr.2021.104268
Abstract: Neutrophils oscillate in number and phenotype after being released from bone marrow. Myocardial infarction (MI) outcome is associated with the time-of-day of ischemia onset. However, the underlying contributive factors of neutrophils to cardiac remodeling post… read more here.
Keywords: neutrophil infiltration; infiltration; myocardial infarction; aged neutrophil ... See more keywords
HMGB1-TLR4-IL23-IL17A axis promotes paraquat-induced acute lung injury by mediating neutrophil infiltration in mice
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-00721-8
Abstract: Paraquat is a poisoning herbicide that primarily targets lung, leading to severe acute lung injury characterized by extensive neutrophil infiltration. However, the mechanisms underlying the neutrophil infiltration is not clear. In this study, we demonstrated… read more here.
Keywords: hmgb1; injury; lung injury; neutrophil infiltration ... See more keywords
Mast Cell Activation Protects Cornea by Promoting Neutrophil Infiltration via Stimulating ICAM-1 and Vascular Dilation in Fungal Keratitis
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-26798-3
Abstract: The role of mast cells (MCs) in fungal infection is largely unknown. This study was to explore a protective role and mechanism of MCs in fungal keratitis. Experimental fungal keratitis (FK) mouse model was developed.… read more here.
Keywords: neutrophil infiltration; vascular dilation; fungal keratitis;
CM-352 EFFICACY IN A MOUSE MODEL OF ANTICOAGULANT-ASSOCIATED INTRACRANIAL HAEMORRHAGE.
Sign Up to like & getrecommendations! Published in 2022 at "Thrombosis and haemostasis"
DOI: 10.1055/a-1759-9962
Abstract: BACKGROUND Intracranial haemorrhage (ICH) is one of the major devastating complications of anticoagulation. Matrix metalloproteinases (MMPs) inhibition has been proposed as a novel pharmacological approach for ICH treatment. OBJECTIVES We evaluated the effects of CM-352… read more here.
Keywords: rivaroxaban; neutrophil infiltration; model; haemorrhage ... See more keywords
Lymph-derived chemokines direct early neutrophil infiltration in the lymph nodes upon Staphylococcus aureus skin infection
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2111726119
Abstract: Significance An efficient innate immune response is essential in the host’s immune protection during infection before adaptive immunity intervenes. We show that the earliest neutrophil infiltration to the lymph node via high endothelial venules is… read more here.
Keywords: lymph flow; neutrophil infiltration; infiltration lymph; infection ... See more keywords
Neutrophil infiltration to the brain is platelet‐dependent, and is reversed by blockade of platelet GPIbα
Sign Up to like & getrecommendations! Published in 2018 at "Immunology"
DOI: 10.1111/imm.12892
Abstract: Neutrophils are key components of the innate immune response, providing host defence against infection and being recruited to non‐microbial injury sites. Platelets act as a trigger for neutrophil extravasation to inflammatory sites but mechanisms and… read more here.
Keywords: neutrophil infiltration; infiltration brain; gpib; brain ... See more keywords
Photodynamic Therapy‐Induced Cyclooxygenase 2 Expression in Tumor‐Draining Lymph Nodes Regulates B‐Cell Expression of Interleukin 17 and Neutrophil Infiltration
Sign Up to like & getrecommendations! Published in 2022 at "Photochemistry and Photobiology"
DOI: 10.1111/php.13601
Abstract: Photodynamic therapy (PDT) is an effective anticancer modality approved by the U.S. Food and Drug Administration (FDA). Antitumor immunity can be augmented during PDT by inducing sterile inflammation in an acute manner, and this process… read more here.
Keywords: draining lymph; neutrophil infiltration; expression; tumor draining ... See more keywords
Lipopolysaccharide (LPS) induced acute lung injury and neuroinflammation in a new mouse model of COVID-19 disease
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733443
Abstract: Objective: Due to their affordability and availability, rodents are the most often employed experimental animals to explore disease mechanisms. Rats and mice's resistance to SARS-CoV-2 infection is impeding a worldwide effort to study the pathogenesis… read more here.
Keywords: covid disease; neutrophil infiltration; lung; physiology ... See more keywords
A secondary wave of neutrophil infiltration causes necrosis and ulceration in lesions of experimental American cutaneous leishmaniasis
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179084
Abstract: We evaluated the importance of neutrophils in the development of chronic lesions caused by L. Viannia spp. using the hamster as experimental model of American Cutaneous Leishmaniasis (ACL). Neutrophils infiltrated the lesion within the first… read more here.
Keywords: neutrophil infiltration; infiltration; american cutaneous; cutaneous leishmaniasis ... See more keywords
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration
Sign Up to like & getrecommendations! Published in 2022 at "EMBO Reports"
DOI: 10.15252/embr.202153608
Abstract: Elevated expression of the X‐linked inhibitor of apoptosis protein (XIAP) has been frequently reported in malignant melanoma suggesting that XIAP renders apoptosis resistance and thereby supports melanoma progression. Independent of its anti‐apoptotic function, XIAP mediates… read more here.
Keywords: neutrophil infiltration; xiap; melanoma; tumour neutrophil ... See more keywords