Bidirectional neutrophil-macrophage interactions as therapeutic leverage points in sepsis.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiaf152
Abstract: Sepsis is a life-threatening condition driven by a dysregulated host response to infection, in which the innate immune axis-particularly the crosstalk between neutrophils and macrophages-plays a central role in dictating disease trajectory. This review delineates… read more here.
Keywords: bidirectional neutrophil; macrophage interactions; macrophage; interactions therapeutic ... See more keywords
Neutrophil-Macrophage Communications via Inflammasome Pathway Induced Graft Injury after LDLT
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation"
DOI: 10.1097/01.tp.0000542807.84197.7c
Abstract: Introduction The shortage of donors urged clinical practitioners to expand the selection criteria to fatty grafts, which are more prone to liver graft injury. Inflammasomes are responsible for acute-phase inflammation after living donor liver transplantation… read more here.
Keywords: graft injury; neutrophil macrophage; injury; macrophage communications ... See more keywords
Neutrophil–macrophage cooperation and its impact on tissue repair
Sign Up to like & getrecommendations! Published in 2019 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12241
Abstract: Immune cells are rapidly recruited to a site of injury or infection. Although the importance of phagocytic immune cells in clearing bacteria has long been appreciated, the advent of technologies allowing more in‐depth analysis of… read more here.
Keywords: tissue repair; neutrophil macrophage; macrophage cooperation; immune cells ... See more keywords
Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0228889
Abstract: Mesenchymal stem cells (MSCs) are a population of pluripotent cells that have been tested for the treatment of many inflammatory diseases. It remains unclear whether MSCs were effective in treating mice with alcoholic hepatitis (AH)… read more here.
Keywords: neutrophil macrophage; hepatic neutrophil; mice; macrophage infiltration ... See more keywords
Interferon regulatory factor 2 binding protein 2b regulates neutrophil versus macrophage fate during zebrafish definitive myelopoiesis
Sign Up to like & getrecommendations! Published in 2019 at "Haematologica"
DOI: 10.3324/haematol.2019.217596
Abstract: Aproper choice of neutrophil-macrophage progenitor cell fate is essential for the generation of adequate myeloid subpopulations during embryonic development and in adulthood. The network governing neutrophil-macrophage progenitor cell fate has several key determinants, such as… read more here.
Keywords: neutrophil macrophage; fate; binding protein; macrophage ... See more keywords
Live Imaging of Heart Injury in Larval Zebrafish Reveals a Multi-Stage Model of Neutrophil and Macrophage Migration
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.579943
Abstract: Neutrophils and macrophages are crucial effectors and modulators of repair and regeneration following myocardial infarction, but they cannot be easily observed in vivo in mammalian models. Hence many studies have utilized larval zebrafish injury models… read more here.
Keywords: neutrophil macrophage; migration; model; larval zebrafish ... See more keywords
Giant phagocytes (Gφ) and neutrophil-macrophage hybrids in human carotid atherosclerotic plaques – An activated phenotype
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1101569
Abstract: Introduction A small subpopulation of CD66b+ neutrophils with extended lifespan and immensely large size was identified in vitro. They internalized dead neutrophil remnants and cellular debris, transforming them into giant phagocytes (Gφ) resembling macrophage-foam cells… read more here.
Keywords: neutrophil macrophage; cd66b cd163; cd66b; giant phagocytes ... See more keywords