O30 Natural compounds affecting neutrophil migration
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2017.06.095
Abstract: Hydrogen peroxide (H 2 O 2 ) has recently been identified as the earliest messenger released by damaged tissues and is crucial for the chemoattraction of neutrophils to sites of injury and infection. However, how… read more here.
Keywords: natural compounds; migration; trpm2; chemotaxis ... See more keywords
Anti-inflammatory effect of the monoterpene myrtenol is dependent on the direct modulation of neutrophil migration and oxidative stress.
Sign Up to like & getrecommendations! Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2017.05.019
Abstract: Myrtenol is a bicyclic monoterpene with anti-inflammatory properties. However, the mechanisms involved are partially unknown. Here, we investigated the effect of myrtenol during experimental chronic arthritis and the possible modulating activity of oxidative stress and… read more here.
Keywords: anti inflammatory; myrtenol; effect; neutrophil migration ... See more keywords
Neutrophil migration in inflammation: intercellular signal relay and crosstalk.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2016.11.002
Abstract: Neutrophils are innate effector cells armed with a potent machinery to combat damage and infection within tissues. Their ability to rapidly respond to danger signals and mobilise is crucial to their role. After extravasation, neutrophil… read more here.
Keywords: signal relay; neutrophil migration; inflammation; crosstalk ... See more keywords
Novel roles for podocalyxin in regulating stress myelopoiesis, Rap1a, and neutrophil migration.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental hematology"
DOI: 10.1016/j.exphem.2017.04.001
Abstract: Podocalyxin (Podxl) is a CD34 orthologue and cell surface sialomucin reported to have roles in renal podocyte diaphragm slit development; vascular cell integrity; and the progression of blood, breast, and prostate cancers. Roles for Podxl… read more here.
Keywords: novel roles; rap1a; stress; podxl ... See more keywords
Trail Formation Alleviates Excessive Adhesion and Maintains Efficient Neutrophil Migration.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c00288
Abstract: Migrating neutrophils are found to leave behind subcellular trails in vivo, but the underlying mechanisms remain unclear. Here, an in vitro cell migration test plus an in vivo observation was applied to monitor neutrophil migration… read more here.
Keywords: adhesion; cell; migration; neutrophil migration ... See more keywords
The stromal cell-derived factor 1/C-X-C chemokine receptor type 4 axis is important in neutrophil migration caused by cardiopulmonary bypass in children.
Sign Up to like & getrecommendations! Published in 2018 at "Interactive cardiovascular and thoracic surgery"
DOI: 10.1093/icvts/ivx358
Abstract: OBJECTIVES Acute lung injury caused by cardiopulmonary bypass (CPB) is characterized by massive neutrophil migration to the lungs. Neutrophil migration may be closely related to stromal cell-derived factor 1 (SDF-1)/C-X-C chemokine receptor Type 4 (CXCR4)… read more here.
Keywords: axis; group; cpb; migration ... See more keywords
Protein kinase D3 promotes neutrophil migration during viral infection
Sign Up to like & getrecommendations! Published in 2022 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12603
Abstract: Protein kinase D (PKD) is a serine/threonine kinase family with three isoforms (PKD1–3) that are expressed in most cells and implicated in a wide array of signaling pathways, including cell growth, differentiation, transcription, secretion, polarization… read more here.
Keywords: viral infection; protein kinase; infection; migration ... See more keywords
Interleukin‐17/interleukin‐17 receptor axis elicits intestinal neutrophil migration, restrains gut dysbiosis and lipopolysaccharide translocation in high‐fat diet‐induced metabolic syndrome model
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1111/imm.13028
Abstract: Sound evidence supports a role for interleukin‐17 (IL‐17) ‐producing γδ T cells and IL‐17‐producing helper T (Th17) cells in intestinal homeostasis, especially in intestinal barrier integrity. In the present study, we aimed to evaluate the… read more here.
Keywords: 17ra mice; translocation; receptor; induced metabolic ... See more keywords
Pathological neutrophil migration predicts adverse outcomes in hospitalized patients with liver cirrhosis
Sign Up to like & getrecommendations! Published in 2022 at "Liver International"
DOI: 10.1111/liv.15486
Abstract: Given the early response of neutrophil granulocytes to infections, detection of pathological neutrophil migration might help in predicting adverse events in patients with liver cirrhosis. read more here.
Keywords: liver cirrhosis; pathological neutrophil; migration predicts; patients liver ... See more keywords
IsoLGs (Isolevuglandins) Drive Neutrophil Migration in Hypertension and Are Essential for the Formation of Neutrophil Extracellular Traps
Sign Up to like & getrecommendations! Published in 2022 at "Hypertension"
DOI: 10.1161/hypertensionaha.122.19305
Abstract: Background: IsoLGs (isolevuglandins) are electrophilic products of lipid peroxidation formed in the presence of reactive oxygen species. IsoLGs contribute to hypertension by an unknown mechanism. Studies have shown that reactive oxygen species production drives the… read more here.
Keywords: isolgs isolevuglandins; netosis; formation neutrophil; hypertension ... See more keywords
ADAM8 signaling drives neutrophil migration and ARDS severity
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.149870
Abstract: Acute respiratory distress syndrome (ARDS) results in catastrophic lung failure and has an urgent, unmet need for improved early recognition and therapeutic development. Neutrophil influx is a hallmark of ARDS and is associated with the… read more here.
Keywords: migration ards; drives neutrophil; severity; neutrophil migration ... See more keywords