Significant elevation of salivary human neutrophil peptides 1-3 levels by probiotic milk in preschool children with severe early childhood caries: a randomized controlled trial.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical oral investigations"
DOI: 10.1007/s00784-020-03606-9
Abstract: OBJECTIVES To determine salivary human neutrophil peptides 1-3 (HNP1-3) levels in caries-free preschool children and in those with early childhood caries (ECC) or severe-ECC, in a daily probiotic group, receiving reconstituted milk with the probiotic… read more here.
Keywords: milk; hnp1; hnp1 levels; salivary human ... See more keywords
Human neutrophil peptides 1-3 protect the murine urinary tract from uropathogenic Escherichia coli challenge
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2206515119
Abstract: Significance Genetic variations can affect the immune response to infectious conditions. Recent evidence shows DNA copy number variations (CNVs) in the DEFA1A3 locus, which encodes for human neutrophil peptides 1-3 (HNP1-3) are associated with urinary… read more here.
Keywords: urinary tract; uropathogenic escherichia; tract; escherichia coli ... See more keywords
Distinctive Roles and Mechanisms of Human Neutrophil Peptides in Experimental Sepsis and Acute Respiratory Distress Syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Critical Care Medicine"
DOI: 10.1097/ccm.0000000000003265
Abstract: Objectives: To examine the effects and mechanisms of human neutrophil peptides in systemic infection and noninfectious inflammatory lung injury. Design: Prospective experimental study. Setting: University hospital-based research laboratory. Subjects: In vitro human cells and in… read more here.
Keywords: sepsis; neutrophil peptides; human neutrophil; injury ... See more keywords
Plasma human neutrophil peptides as biomarkers of disease severity and mortality in patients with decompensated cirrhosis
Sign Up to like & getrecommendations! Published in 2023 at "Liver International"
DOI: 10.1111/liv.15520
Abstract: Human neutrophil peptides (HNP)‐1, ‐2 and ‐3 are the most abundant proteins in neutrophil azurophilic granules and are rapidly released via neutrophil degranulation upon activation. The aims of our study were to assess the role… read more here.
Keywords: decompensated cirrhosis; human neutrophil; patients decompensated; biomarkers disease ... See more keywords