Piezoelectric‐Enhanced Nanocatalysts Trigger Neutrophil N1 Polarization against Bacterial Biofilm by Disrupting Redox Homeostasis
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DOI: 10.1002/adma.202409633
Abstract: Strategies of manipulating redox signaling molecules to inhibit or activate immune signals have revolutionized therapeutics involving reactive oxygen species (ROS). However, certain diseases with dual resistance barriers to the attacks by both ROS and immune… read more here.
Keywords: redox homeostasis; neutrophil polarization; biofilm; bacterial biofilm ... See more keywords
Hypoxia Microenvironment Preconditioning Attenuated Myocardial Ischemia‐Reperfusion Injury via Stc1‐Mediating Cardiomyocyte Self‐Protection and Neutrophil Polarization
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DOI: 10.1002/advs.202411880
Abstract: Ischemic preconditioning (IPC) therapy application to attenuate myocardial ischemia‐reperfusion (MI/R) injury in clinical practice remains challenging. The secretome, derived from hypoxia‐preconditioned cardiomyocytes (SHPC), potentially mimics the IPC microenvironment and facilitates IPC clinical translation. This study… read more here.
Keywords: neutrophil polarization; microenvironment; hypoxia; injury ... See more keywords
Stretched Vascular Endothelial Cells Polarized Neutrophils to N2 Type via TRPC1-IL13-STAT3 Axis.
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DOI: 10.1111/odi.15168
Abstract: OBJECTIVE VECs play a crucial role in regulating the function of neutrophils, which is essential for immune responses and inflammation. As stretch-sensitive cells, VECs sense mechanical stretch through surface mechanoreceptors, converting external mechanical stimuli into… read more here.
Keywords: vascular endothelial; neutrophil polarization; stretched vascular; trpc1 ... See more keywords