Transfusable neutrophil progenitors as cellular therapy for the prevention of invasive fungal infections.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of leukocyte biology"
DOI: 10.1002/jlb.4hi1221-722r
Abstract: The use of mature neutrophil (granulocyte) transfusions for the treatment of neutropenic patients with invasive fungal infections (IFIs) has been the focus of multiple clinical trials. Despite these efforts, the transfusion of mature neutrophils has… read more here.
Keywords: mature neutrophils; fungal infections; neutrophil progenitors; invasive fungal ... See more keywords
Abstract 5956: Tumor-infiltrating neutrophil progenitors impair homologous DNA repair and promote sensitivity to PARP-inhibition
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5956
Abstract: Tumor evolution is one of the major mechanisms responsible for acquiring therapy-resistant and more aggressive cancer clones. Whether the tumor microenvironment through immune-mediated mechanisms might promote the development of more aggressive cancer types is crucial… read more here.
Keywords: dna repair; tumor infiltrating; neutrophil progenitors; tumor ... See more keywords