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Published in 2017 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2017.00243
Abstract: More than two decades after cloning the cystic fibrosis transmembrane regulator (CFTR) gene, the defective gene in cystic fibrosis (CF), we still do not understand how dysfunction of this ion channel causes lung disease and…
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Keywords:
neutrophil survival;
cystic fibrosis;
pseudomonas aeruginosa;
infection ... See more keywords
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Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.889290
Abstract: Neutrophils are the most abundant and shortest-lived leukocytes in humans and tight regulation of neutrophil turnover via constitutive apoptosis is essential for control of infection and resolution of inflammation. Accordingly, aberrant neutrophil turnover is hallmark…
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Keywords:
pi3k;
survival signaling;
neutrophil survival;
infection ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.726153
Abstract: Phagocytosis, degranulation, and neutrophil extracellular traps (NETs) formation build the armory of neutrophils for the first line of defense against invading pathogens. All these processes are modulated by the microenvironment including tonicity, pH and oxygen…
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Keywords:
infarction;
myocardial infarction;
hypoxia promotes;
neutrophil survival ... See more keywords