Articles with "neutrophilia inflammation" as a keyword



Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation

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Published in 2021 at "Nature Cell Biology"

DOI: 10.1038/s41556-021-00774-y

Abstract: Defective silencing of retrotransposable elements has been linked to inflammageing, cancer and autoimmune diseases. However, the underlying mechanisms are only partially understood. Here we implicate the histone H3.3 chaperone Daxx, a retrotransposable element repressor inactivated… read more here.

Keywords: neutrophilia inflammation; chromatin landscape; chaperone daxx; daxx haematopoietic ... See more keywords