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Published in 2025 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.70026
Abstract: Treatment options for Type 1 Gaucher Disease (GD1) include enzyme replacement therapy and oral substrate reduction therapy. The criteria for treatment initiation vary across regions. Recent retrospective studies have highlighted the natural progression of never‐treated…
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Keywords:
never treated;
non splenectomised;
prospective follow;
gaucher disease ... See more keywords
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Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-0828-4
Abstract: Though gray matter deficits have been consistently revealed in chronic treated schizophrenia, it is still not clear whether there are different brain alterations between chronic never treated and treated patients. To explore the different patterns…
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Keywords:
matter alterations;
never treated;
treated chronic;
gray matter ... See more keywords
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Published in 2018 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2018.1529780
Abstract: ABSTRACT Left atrial (LA) strain is known to exhibit an early progressive reduction in hypertensive patients with diastolic dysfunction. However, an association of the renin-angiotensin-*aldosterone system (RAAS) with LA deformation has not been found in…
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Keywords:
never treated;
blood pressure;
deformation;
strain ... See more keywords
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Published in 2022 at "Cerebral cortex"
DOI: 10.1093/cercor/bhac474
Abstract: Alterations of radiomic features (RFs) in gray matter are observed in schizophrenia, of which the results may be limited by small study samples and confounding effects of drug therapies. We tested for RFs alterations of…
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Keywords:
matter;
matter never;
never treated;
gray matter ... See more keywords
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Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000836516.61791.fb
Abstract: Objective: Non-alcoholic fatty liver disease (NAFLD) is closely related to the metabolic syndrome, arterial hypertension and overall cardiovascular (CV) disease. We aimed to investigate if those first diagnosed and never-treated patients with essential hypertension at…
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Keywords:
first diagnosed;
hypertension;
diagnosed never;
group ... See more keywords
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Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000836520.70681.cb
Abstract: Objective: Endothelial dysfunction may be estimated by reduced endothelial glycocalyx (EG). However, the role of EG as a hypertension mediated organ damage (HMOD) still remains controversial. Cigarette smoking represents a significant CV risk factor. Aim…
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Keywords:
first diagnosed;
male;
hypertension;
diagnosed never ... See more keywords
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Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000836524.41792.04
Abstract: Objective: Isolated diastolic hypertension (IDH) usually remains untreated as it is considered benign compared to isolated systolic or combined systolic/diastolic hypertension. Hypertension mediated organ damage (HMOD) needs to be assessed in each individual hypertensive patient…
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Keywords:
first diagnosed;
hypertension;
diagnosed never;
never treated ... See more keywords
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Published in 2024 at "BMJ Global Health"
DOI: 10.1136/bmjgh-2024-015671
Abstract: Introduction Five of the neglected tropical diseases use a strategy of preventative chemotherapy distributed via mass drug administration (MDA) for all eligible people living in endemic areas. To be successful, high coverage must be sustained…
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Keywords:
never treated;
mass drug;
drug administration;
study ... See more keywords
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Published in 2021 at "BMC Psychiatry"
DOI: 10.1186/s12888-021-03552-0
Abstract: Background The corpus callosum (CC) deficits have been well documented in chronic schizophrenia. However, the long-term impacts of antipsychotic monotherapies on callosal anatomy remain unclear. This cross-sectional study sought to explore micro- and macro-structural characteristics…
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Keywords:
schizophrenia;
clozapine;
chronic schizophrenia;
corpus callosum ... See more keywords