Trichomonicidal activity of a new anthraquinone isolated from the roots of Morinda panamensis Seem
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development Research"
DOI: 10.1002/ddr.21504
Abstract: Trichomoniasis, caused by the protozoan parasite Trichomonas vaginalis, is the most common nonviral sexually transmitted infection worldwide. Although drug treatment is available, unpleasant side effects and increased resistance to the nitroimidazole family have been documented.… read more here.
Keywords: roots morinda; new anthraquinone; morinda panamensis; isolated roots ... See more keywords
Selective Inhibition of PTP1B by New Anthraquinone Glycosides from Knoxia valerianoides.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.2c00879
Abstract: Protein tyrosine phosphatase 1B (PTP1B) is highly validated as a therapeutic target for type 2 diabetes. However, active site-directed PTP1B inhibitors generally suffer from poor selectivity and bioavailability. Inspired by the identification of a unique… read more here.
Keywords: selective inhibition; knoxia valerianoides; inhibition ptp1b; anthraquinone glycosides ... See more keywords
A new anthraquinone and a new naphthoquinone from the whole plant of Spermacoce latifolia
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2017.1279609
Abstract: Abstract A phytochemical study on the whole plant of Spermacoce latifolia led to the isolation of a new anthraquinone, 1,2,6-trihydroxy-5-methoxy-9,10-anthraquinone (1), and a new naphthoquinone, (2R)-6-hydroxy-7-methoxy-dehydroiso-α-lapachone (2), together with three known anthraquinones (3–5). Their structures… read more here.
Keywords: plant spermacoce; new anthraquinone; whole plant; anthraquinone new ... See more keywords