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Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.8b00949
Abstract: Ever since the discovery of the new antibiotic teixobactin, studies of its structure-activity relationships have never ceased. Here we focus on the chirality of the threonine (Thr) residue, which belongs to the ring motif of…
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Keywords:
teixobactin;
antibiotic teixobactin;
necessity thr;
new antibiotic ... See more keywords
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Published in 2025 at "Protein and peptide letters"
DOI: 10.2174/0109298665356946241218103145
Abstract: Like other vertebrates, amphibians possess innate and adaptive immune systems. At the center of the adaptive immune system is the Major Histocompatibility Complex. The important molecules of innate immunity are antimicrobial peptides (AMPs). These peptides…
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Keywords:
new antibiotic;
innate immunity;
amphibian derived;
development ... See more keywords
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Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.578823
Abstract: Background: Infection is a disease that can occur due to the entrance of a virus, bacteria, and other infectious agents. Cefiderocol is innovative cephalosporin drug that belongs to a special class of antibiotics, sideromycins, which…
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Keywords:
new antibiotic;
gram negative;
burden serious;
serious difficult ... See more keywords
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Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11091198
Abstract: Since the discovery of streptomycin, actinomycetes have been a useful source for new antibiotics, but there have been diminishing rates of new finds since the 1960s. The decreasing probability of identifying new active agents led…
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Keywords:
mechanism based;
antibiotic producers;
new antibiotic;
mechanism ... See more keywords