Articles with "new antibiotic" as a keyword



The Necessity of d-Thr in the New Antibiotic Teixobactin: A Molecular Dynamics Study

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Published in 2019 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.8b00949

Abstract: Ever since the discovery of the new antibiotic teixobactin, studies of its structure-activity relationships have never ceased. Here we focus on the chirality of the threonine (Thr) residue, which belongs to the ring motif of… read more here.

Keywords: teixobactin; antibiotic teixobactin; necessity thr; new antibiotic ... See more keywords

Amphibian-Derived Antimicrobial Peptides: Essential Components of Innate Immunity and Potential Leads for New Antibiotic Development.

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Published in 2025 at "Protein and peptide letters"

DOI: 10.2174/0109298665356946241218103145

Abstract: Like other vertebrates, amphibians possess innate and adaptive immune systems. At the center of the adaptive immune system is the Major Histocompatibility Complex. The important molecules of innate immunity are antimicrobial peptides (AMPs). These peptides… read more here.

Keywords: new antibiotic; innate immunity; amphibian derived; development ... See more keywords
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The Burden of the Serious and Difficult-to-Treat Infections and a New Antibiotic Available: Cefiderocol

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Published in 2020 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2020.578823

Abstract: Background: Infection is a disease that can occur due to the entrance of a virus, bacteria, and other infectious agents. Cefiderocol is innovative cephalosporin drug that belongs to a special class of antibiotics, sideromycins, which… read more here.

Keywords: new antibiotic; gram negative; burden serious; serious difficult ... See more keywords

Mechanism-Based Approach to New Antibiotic Producers Screening among Actinomycetes in the Course of the Citizen Science Project

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Published in 2022 at "Antibiotics"

DOI: 10.3390/antibiotics11091198

Abstract: Since the discovery of streptomycin, actinomycetes have been a useful source for new antibiotics, but there have been diminishing rates of new finds since the 1960s. The decreasing probability of identifying new active agents led… read more here.

Keywords: mechanism based; antibiotic producers; new antibiotic; mechanism ... See more keywords