Institutional Experience With New Antidiabetic Drugs in Kidney Transplant.
Sign Up to like & getrecommendations! Published in 2021 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2021.08.042
Abstract: BACKGROUND The recent introduction of new antidiabetic drugs, analogs of glucagon-like peptide-1 (GLP-1) and sodium-glucose cotransporter 2 inhibitors, has shown excellent results in the management of patients with diabetes with chronic kidney disease. However, documented… read more here.
Keywords: antidiabetic drugs; new antidiabetic; kidney transplant; institutional experience ... See more keywords
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c02093
Abstract: A new series of analogues or derivatives of the previously reported PPARα/γ dual agonist LT175 allowed the identification of ligand 10, which was able to potently activate both PPARα and -γ subtypes as full and… read more here.
Keywords: pyruvate carrier; inhibition; mitochondrial pyruvate; new antidiabetic ... See more keywords
Two new antidiabetic xanthones from the twigs of Garcinia oblongifolia.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2055016
Abstract: Two new xanthones, oblongixanthones I (1) and J (2), and seven known compounds (3-9), were isolated from an EtOAc extract of the twigs of Garcinia oblongifolia. Their structures were elucidated using spectroscopic methods, mainly 1 D… read more here.
Keywords: antidiabetic xanthones; twigs garcinia; xanthones twigs; two new ... See more keywords