Synthesis and Antimicrobial Evaluations of New 5-aryl Linked Bispyrazolines
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DOI: 10.1002/jhet.2583
Abstract: Syntheses of new bispyrazolines 4a, 4b, 4c, 4d, 4e, 4f, 4g built around the aliphatic linkers of varying lengths have been described. The intermediate bischalcones and final bishetrocyclics were also evaluated for their antimicrobial activities. read more here.
Keywords: aryl linked; new aryl; antimicrobial evaluations; synthesis antimicrobial ... See more keywords
Design, synthesis, and biological evaluation of new 1-aryl-4-(β-D-fructopyranos-3-O-yl)methyl-1H-1,2,3-triazole derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-018-2319-6
Abstract: New 1-aryl-4-(β-D-fructopyranos-3-O-yl)methyl-1H-1,2,3-triazole derivatives have been synthesized by a CuAAC reaction and their antibacterial and antifungal activity has been evaluated. Some of the derivatives showed remarkable in vitro antibacterial activity against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas… read more here.
Keywords: methyl triazole; aryl fructopyranos; design synthesis; fructopyranos methyl ... See more keywords
Design and Synthesis of New 5-aryl-4-Arylethynyl-1H-1,2,3-triazoles with Valuable Photophysical and Biological Properties
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DOI: 10.3390/molecules26092801
Abstract: Cu-catalyzed 1,3-dipolar cycloaddition of methyl 2-azidoacetate to iodobuta-1,3-diynes and subsequent Suzuki-Miyaura cross-coupling were used to synthesize new triazoles derivatives: 5-aryl-4-arylethynyl-1H-1,2,3-triazoles. Investigation of their optical properties by using UV absorption and fluorescence emission spectroscopies revealed that… read more here.
Keywords: design synthesis; triazoles valuable; synthesis new; new aryl ... See more keywords
New 5-Aryl-1,3,4-Thiadiazole-Based Anticancer Agents: Design, Synthesis, In Vitro Biological Evaluation and In Vivo Radioactive Tracing Studies
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DOI: 10.3390/ph15121476
Abstract: A new series of 5-(4-chlorophenyl)-1,3,4-thiadiazole-based compounds featuring pyridinium (3), substituted piperazines (4a–g), benzyl piperidine (4i), and aryl aminothiazoles (5a–e) heterocycles were synthesized. Evaluation of the cytotoxicity potential of the new compounds against MCF-7 and HepG2… read more here.
Keywords: thiadiazole based; evaluation; radioactive tracing; new aryl ... See more keywords