The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders"
DOI: 10.1002/mds.27718
Abstract: We recently demonstrated that NLY01, a novel glucagon‐like peptide‐1 receptor agonist, exerts neuroprotective effects in two mouse models of PD in a glia‐dependent manner. NLY01 prevented microglia from releasing inflammatory mediators known to convert astrocytes… read more here.
Keywords: avenues pharmacological; paradigm new; new avenues; neurodegeneration ... See more keywords
Fungal Cellulases: New Avenues in Biofuel Production
Sign Up to like & getrecommendations! Published in 2019 at "Fungal Biology"
DOI: 10.1007/978-3-030-14726-6_1
Abstract: Cellulases are the enzymes decaying cellulose and related polysaccharides and are produced by organisms like fungi, bacteria, algae, and protozoans. Fungi are the pioneers behind cellulose degradation, and the fungal cellulases are simpler compared to… read more here.
Keywords: production; new avenues; fungal cellulases; industry ... See more keywords
New avenues for NASH therapy by targeting ACC.
Sign Up to like & getrecommendations! Published in 2022 at "Cell metabolism"
DOI: 10.1016/j.cmet.2022.01.001
Abstract: Acetyl-CoA carboxylase (ACC) is one of the more promising therapeutic targets for non-alcoholic steatohepatitis (NASH), but current ACC inhibitors already tested in clinical trials also exert the unwanted adverse side effect of hypertriglyceridemia. In two… read more here.
Keywords: medicine; avenues nash; nash therapy; new avenues ... See more keywords
Exploring new avenues for modifying course of progression of Alzheimer's disease: The rise of natural medicine
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2021.117332
Abstract: With a constantly growing elderly population worldwide, a focus on developing efficient prevention and therapy for Alzheimer's disease (AD) seems timely and topical. Emphasis on natural medicine is increasingly popular in the search for drug… read more here.
Keywords: medicine; exploring new; new avenues; alzheimer disease ... See more keywords
New avenues for increasing yield and stability in C3 cereals: exploring ear photosynthesis.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in plant biology"
DOI: 10.1016/j.pbi.2020.01.001
Abstract: Small grain cereals such as wheat, rice and barley are among the most important crops worldwide. Any attempt to increase crop productivity and stability through breeding implies developing new strategies for plant phenotyping, including defining… read more here.
Keywords: new avenues; increasing yield; photosynthesis; ear photosynthesis ... See more keywords
New avenues for thermal inversions in atmospheres of hot Jupiters
Sign Up to like & getrecommendations! Published in 2019 at "Monthly Notices of the Royal Astronomical Society"
DOI: 10.1093/mnras/stz751
Abstract: Thermal emission spectra of hot Jupiters have led to key constraints on thermal inversions (or 'stratospheres') in their atmospheres with important implications for their atmospheric processes. Canonically, thermal inversions in hot Jupiters have been suggested… read more here.
Keywords: thermal inversions; new avenues; inversions atmospheres; visible absorbers ... See more keywords
New Avenues to Design Toxoplasma Vaccines Based on Oocysts and Cysts
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.910961
Abstract: Toxoplasmosis is a worldwide disease affecting all warm-blooded animals, including humans. Vaccination strategies aimed at inducing an efficient immune response while preventing transmission have been attempted in the past. While many different approaches can partially… read more here.
Keywords: avenues design; new avenues; vaccines based; toxoplasma ... See more keywords
miR-aculous new avenues for cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.929677
Abstract: The rising toll of cancer globally necessitates ingenuity in early detection and therapy. In the last decade, the utilization of immune signatures and immune-based therapies has made significant progress in the clinic; however, clinical standards… read more here.
Keywords: new avenues; immunotherapy; immune cancer; mir aculous ... See more keywords
New Avenues of Heme Synthesis Regulation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137467
Abstract: During erythropoiesis, there is an enormous demand for the synthesis of the essential cofactor of hemoglobin, heme. Heme is synthesized de novo via an eight enzyme-catalyzed pathway within each developing erythroid cell. A large body… read more here.
Keywords: new avenues; heme synthesis; synthesis; regulation ... See more keywords
Chromatographic-Based Platforms as New Avenues for Scientific Progress and Sustainability
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27165267
Abstract: Chromatography was born approximately one century ago and has undergone outstanding technological improvements in innovation, research, and development since then that has made it fundamental to advances in knowledge at different levels, with a relevant… read more here.
Keywords: new avenues; based platforms; avenues scientific; sustainability ... See more keywords
New Avenues of Research for Nanoparticle Drug Delivery Systems
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12234141
Abstract: Knowledge of the different elements that determine the optimal method for drug loading and delivery nanosystems using nanoparticles of different natures is experiencing a remarkable boom in many scientific fields, especially in medicine, chemistry, biology,… read more here.
Keywords: new avenues; research nanoparticle; avenues research; nanoparticle drug ... See more keywords