Articles with "new chemotypes" as a keyword



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Scaffold-Hopping Approach To Identify New Chemotypes of Dimpropyridaz.

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Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c00636

Abstract: Dimpropyridaz is a pyrazole carboxamide insecticide with a novel mode of action, currently under worldwide development by BASF, providing excellent activity against sucking pests. A series of dimpropyridaz analogues were designed to investigate the impact… read more here.

Keywords: chemotypes dimpropyridaz; approach identify; new chemotypes; identify new ... See more keywords
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Advances in the discovery of new chemotypes through ultra-large library docking

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Published in 2023 at "Expert Opinion on Drug Discovery"

DOI: 10.1080/17460441.2023.2171984

Abstract: ABSTRACT Introduction The size and complexity of virtual screening libraries in drug discovery have skyrocketed in recent years, reaching up to multiple billions of accessible compounds. However, virtual screening of such ultra-large libraries poses several… read more here.

Keywords: chemotypes ultra; discovery new; virtual screening; ultra large ... See more keywords
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New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27103097

Abstract: Antimicrobial resistance (AMR) poses a serious threat to our society from both the medical and economic point of view, while the antibiotic discovery pipeline has been dwindling over the last decades. Targeting non-essential bacterial pathways,… read more here.

Keywords: inhibition ppgpp; quest new; chemotypes inhibition; new chemotypes ... See more keywords