Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands
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DOI: 10.3390/molecules28031156
Abstract: The chemokine receptor CXCR4 and its ligand CXCL12 regulate leukocyte trafficking, homeostasis and functions and are potential therapeutic targets in many diseases such as HIV-1 infection and cancers. Here, we identified new CXCR4 ligands in… read more here.
Keywords: cxcr4 ligands; bis imidazoline; alkyl chain; new cxcr4 ... See more keywords