New cytotoxic tricycloalternarenes from fungus Alternaria brassicicola.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103279
Abstract: Seven previously undescribed metabolites, designated as tricycloalternarenes Q-W (1-7), were isolated and identified from the fermented rice substrate of fungus Alternaria brassicicola. The planar and absolute structures of all new compounds were determined on the… read more here.
Keywords: new cytotoxic; cytotoxic tricycloalternarenes; fungus alternaria; alternaria brassicicola ... See more keywords
A new cytotoxic salannin-class limonoid alkaloid from seeds of Azadirachta indica A. Juss
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2017.11.042
Abstract: Abstract A new cytotoxic salannin-class limonoid alkaloid, azadiramide A (1), was isolated from seeds of Azadirachta indica A. Juss. Its structure was elucidated by extensive analysis of spectroscopic data and quantum chemical calculation. Compound 1… read more here.
Keywords: new cytotoxic; salannin class; limonoid alkaloid; class limonoid ... See more keywords
Pogostemins A-C, three new cytotoxic meroterpenoids from Pogostemon auricularius.
Sign Up to like & getrecommendations! Published in 2018 at "Fitoterapia"
DOI: 10.1016/j.fitote.2018.08.015
Abstract: Pogostemins A-C (1-3), three new meroterpenoids with pyrone-sesquiterpenoid hybrid skeletons, were isolated from the aerial parts of Pogostemon auricularius. Their chemical structures were elucidated by 1D- and 2D-NMR and HRESIMS analyses. Compound 1 showed significant… read more here.
Keywords: pogostemon auricularius; meroterpenoids pogostemon; new cytotoxic; cytotoxic meroterpenoids ... See more keywords
New cytotoxic steroidal saponins from Cestrum parqui
Sign Up to like & getrecommendations! Published in 2017 at "Phytochemistry Letters"
DOI: 10.1016/j.phytol.2017.09.022
Abstract: Abstract Two new steroidal saponins, 25(R)-3β [( O -β- d -glucopyranosyl-(1 → 3)-β- d -glucopyranosyl-(1 → 2)- O -[β- d -xylopyranosyl-(1 → 3)- O -β- d -glucopyranosyl-(1 → 4)-β- d -galactopyranosyl)oxy]-5α, 15β, 22 R , 25 R -spirostan-3,15-diol ( 1, named parquispiroside )… read more here.
Keywords: steroidal saponins; new cytotoxic; cestrum parqui; cytotoxic steroidal ... See more keywords
Seven new cytotoxic phenylspirodrimane derivatives from the endophytic fungus Stachybotrys chartarum
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c8ra10195g
Abstract: The diverse structures and anticancer activities of phenylspirodrimane derivatives are investigated. read more here.
Keywords: new cytotoxic; endophytic fungus; phenylspirodrimane derivatives; cytotoxic phenylspirodrimane ... See more keywords
New Cytotoxic Cycloartane Triterpenes from the Aerial Parts of Actaea heracleifolia (syn. Cimicifuga heracleifolia).
Sign Up to like & getrecommendations! Published in 2019 at "Planta medica"
DOI: 10.1055/a-0733-7229
Abstract: One new 15,16-seco-cycloartane triterpene (1: ), three new cycloartane triterpene glycosides (2: -4: ), and five known compounds (5: -9: ) were isolated from the aerial parts of Actaea heracleifolia. The chemical structures of these… read more here.
Keywords: parts actaea; new cytotoxic; cytotoxic cycloartane; cycloartane ... See more keywords
Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora.
Sign Up to like & getrecommendations! Published in 2021 at "Planta medica"
DOI: 10.1055/a-1530-1128
Abstract: Two new maytansinoids, N-methyltreflorine (1: ) and methyltrewiasine (2: ), were isolated from the dried fruits of Trewia nudiflora, together with three known congeners (3: - 5: ). Their structures were elucidated by spectroscopic methods, and… read more here.
Keywords: new cytotoxic; cytotoxic maytansinoids; two new; maytansinoids targeting ... See more keywords
A new cytotoxic 12-membered macrolactone from the endophytic fungus Exserohilum rostratum LPC-001
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2018.1518322
Abstract: Abstract A new oxacyclododecindione-type macrolactone, (13R,14S,15R)-13-hydroxy-14-deoxyoxacyclododecindione (1), has been obtained from the solid cultures of the fungus Exserohilum rostratum, a fungal strain endophytic in Gymnadenia conopsea. Its structure, including the absolute configuration, was extensively established… read more here.
Keywords: membered macrolactone; fungus exserohilum; new cytotoxic; exserohilum rostratum ... See more keywords
A new cytotoxic indole alkaloid from the fungus Penicillium polonicum TY12.
Sign Up to like & getrecommendations! Published in 2020 at "Natural product research"
DOI: 10.1080/14786419.2020.1828406
Abstract: A new dimeric monoterpene indole alkaloid polonidine A (1), along with five known compounds, cyclopenol (2), verrucosidin (3), fructigenine A (4), 3-O-methylviridicatin (5) and aurantiomides C (6), were isolated from Penicillium polonicum TY12. Their structures… read more here.
Keywords: penicillium polonicum; indole alkaloid; polonicum ty12; new cytotoxic ... See more keywords
Withalutin, a new cytotoxic withanolide from Athenaea velutina (Sendtn.) D’Arcy
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Research"
DOI: 10.1080/14786419.2022.2039135
Abstract: Abstract Bioassay-guided fractionation of dichloromethane extract from Athenaea velutina leaves led to the isolation of three withanolides, all being reported for the first time in this species. They were identified as withacnistin (1), withacnistin acetate… read more here.
Keywords: withanolide athenaea; athenaea velutina; withalutin new; new cytotoxic ... See more keywords
Three new cytotoxic stilbene dimers from paphiopedilum dianthum.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2101049
Abstract: Three new stilbene dimers, paphiodianthins A-C (1-3), and nine known stilbenes, lignan and flavonoids (4-12) were isolated from the roots and leaves of Paphiopedilum dianthum (Orchidaceae). The structures of new compounds were elucidated from their… read more here.
Keywords: new cytotoxic; stilbene dimers; paphiopedilum dianthum; three new ... See more keywords