A new Drosophila model of Ubiquilin knockdown shows the effect of impaired proteostasis on locomotive and learning abilities
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DOI: 10.1016/j.yexcr.2017.12.010
Abstract: &NA; Ubiquilin (UBQLN) plays a crucial role in cellular proteostasis through its involvement in the ubiquitin proteasome system and autophagy. Mutations in the UBQLN2 gene have been implicated in amyotrophic lateral sclerosis (ALS) and ALS… read more here.
Keywords: drosophila model; proteostasis; impaired proteostasis; new drosophila ... See more keywords