FSCN1 as a new druggable target in adrenocortical carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34526
Abstract: Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with a high risk of relapse and metastatic spread. The actinâbundling protein fascin (FSCN1) is overexpressed in aggressive ACC and represents a reliable prognostic indicator. FSCN1 has… read more here.
Keywords: new druggable; druggable target; acc; adrenocortical carcinoma ... See more keywords
New Druggable Targets for Rheumatoid Arthritis Based on Insights From Synovial Biology
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.834247
Abstract: Rheumatoid arthritis (RA) is a multifactorial autoimmune disease characterized by chronic inflammation and destruction of multiple small joints which may lead to systemic complications. Altered immunity via pathogenic autoantibodies pre-date clinical symptom development by several… read more here.
Keywords: new druggable; rheumatoid arthritis; synovial biology; druggable targets ... See more keywords