New genetic prognostic biomarkers in primary central nervous system lymphoma (PCNSL)
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2061
Abstract: PCNSL is a rare extranodal NHL with poor prognosis. Tumorigenesis has been associated with hyperactivation of BCR downstream and NFkB pathways. We studied the prognosis of the relative expression profile of target genes of NFkB… read more here.
Keywords: genetic prognostic; new genetic; central nervous; prognostic biomarkers ... See more keywords
Synthetic genome recoding: new genetic codes for new features
Sign Up to like & getrecommendations! Published in 2017 at "Current Genetics"
DOI: 10.1007/s00294-017-0754-z
Abstract: Full genome recoding, or rewriting codon meaning, through chemical synthesis of entire bacterial chromosomes has become feasible in the past several years. Recoding an organism can impart new properties including non-natural amino acid incorporation, virus… read more here.
Keywords: new genetic; genome recoding; genetic codes; synthetic genome ... See more keywords
New genetic causes for complex hereditary spastic paraplegia
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2017.06.019
Abstract: INTRODUCTION Hereditary Spastic Paraplegia (HSP) represents a complex and heterogeneous group of rare neurodegenerative disorders that share a common clinical feature of weakness and lower limb spasticity that can occur alone or in combination with… read more here.
Keywords: new genetic; hereditary spastic; spastic paraplegia; genetic causes ... See more keywords
Characterization of the new genetic variant in the caprine lipoprotein lipase gene
Sign Up to like & getrecommendations! Published in 2020 at "Small Ruminant Research"
DOI: 10.1016/j.smallrumres.2019.10.012
Abstract: Abstract Lipoprotein Lipase (LPL), a key enzyme in lipid metabolism, catalyses the hydrolysis of triglycerides (TG) from TG-rich lipoproteins, and serves a bridging function that enhances the cellular uptake of lipoproteins. By sequencing, we identified… read more here.
Keywords: new genetic; variant caprine; lipase; genetic variant ... See more keywords
Hypertension: A new genetic clue to unravel the origins of pre-eclampsia
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Nephrology"
DOI: 10.1038/nrneph.2017.116
Abstract: Pre-eclampsia is a common disorder of pregnancy for which the underlying mechanism is poorly understood. A genome-wide association study has now identified a pre-eclampsia susceptibility locus located near the FLT1 gene. This study brings us… read more here.
Keywords: clue unravel; new genetic; pre eclampsia; unravel origins ... See more keywords
Multi-level genomic analyses suggest new genetic variants involved in human memory
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-018-0201-8
Abstract: Development of high-throughput genotyping platforms provides an opportunity to identify new genetic elements related to complex cognitive functions. Taking advantage of multi-level genomic analysis, here we studied the genetic basis of human short-term (STM, n = 1623)… read more here.
Keywords: new genetic; term; multi level; level genomic ... See more keywords
New Genetic Operators for Searching for S-Boxes with Low Boomerang Uniformity
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Access"
DOI: 10.1109/access.2022.3144458
Abstract: The boomerang uniformity measures the resistance of block ciphers to boomerang attacks and has become an essential criterion of the substitution box (S-box). However, the S-boxes created by the Feistel structure have a poor property… read more here.
Keywords: new genetic; genetic algorithm; boomerang uniformity; genetic operators ... See more keywords
New genetic and clinical features of neonatal inflammatory skin and bowel disease 1
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Dermatology"
DOI: 10.1111/bjd.21589
Abstract: ment on phenotypes of pustular psoriasis. J Eur Acad Dermatol Venereol 2017; 31:1792–9. 7 Fujita H, Terui T, Hayama K et al. Japanese guidelines for the management and treatment of generalized pustular psoriasis: the new… read more here.
Keywords: new genetic; generalized pustular; genetic clinical; pustular psoriasis ... See more keywords
Large-Scale Phylogenetic Analysis Reveals a New Genetic Clade among Escherichia coli O26 Strains
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02525-21
Abstract: Shiga toxin-producing Escherichia coli (STEC) O26 is the second prevalent STEC serogroup only to O157, which can cause a series of diseases ranging from mild diarrhea to life-threatening hemolytic uremic syndrome (HUS). The serogroup is… read more here.
Keywords: analysis; escherichia coli; large scale; new genetic ... See more keywords
Genes for the high life: New genetic variants point to positive selection for high altitude hypoxia in Tibetans
Sign Up to like & getrecommendations! Published in 2017 at "Zoological Research"
DOI: 10.24272/j.issn.2095-8137.2017.031
Abstract: People living on the high plateaus of the world have long fascinated biological anthropologists and geneticists because they live in “thin air” and epitomize an extreme of human biological adaptation. Far from posing obstacles to… read more here.
Keywords: new genetic; positive selection; genetic variants; altitude ... See more keywords
A new genetic strategy for targeting microglia in development and disease
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.54590
Abstract: As the resident macrophages of the brain and spinal cord, microglia are crucial for the phagocytosis of infectious agents, apoptotic cells and synapses. During brain injury or infection, bone-marrow derived macrophages invade neural tissue, making… read more here.
Keywords: microglia; development; development disease; targeting microglia ... See more keywords