Ionospheric annual anomaly—New insights to the physical mechanisms
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Geophysical Research"
DOI: 10.1002/2017ja024170
Abstract: The ionospheric annual anomaly or nonseasonal anomaly of the ionosphere is characterized by globally increased ionization in December solstice than in June solstice. Though this phenomenon was reported several decades ago, the causal mechanisms have… read more here.
Keywords: ionospheric annual; physical mechanisms; anomaly new; new insights ... See more keywords
New insights into the morphogenesis of the gubernaculum testis and the inguinal canal
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Anatomy"
DOI: 10.1002/ca.22880
Abstract: There is no consensus about the role of the gubernaculum testis (GT). Nineteen human embryos (Carnegie stages 15–23), 36 fetuses (9 weeks to term), and eight neonates were examined. All the embryos and 25 fetuses… read more here.
Keywords: inguinal canal; insights morphogenesis; new insights; gubernaculum testis ... See more keywords
New insights into molecules and pathways of cancer metabolism and therapeutic implications
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Communications"
DOI: 10.1002/cac2.12112
Abstract: Cancer cells are abnormal cells that can reproduce and regenerate rapidly. They are characterized by unlimited proliferation, transformation and migration, and can destroy normal cells. To meet the needs for cell proliferation and migration, tumor… read more here.
Keywords: insights molecules; metabolism; tumor cells; new insights ... See more keywords
New Insights into Tolytoxin Effect in Human Cancer Cells: Apoptosis Induction and the Relevance of Hydroxyl Substitution of Its Macrolide Cycle on Compound Potency
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100489
Abstract: Scytophycins, including tolytoxin, represent a class of actin disrupting macrolides with strong antiproliferative effects on human cells. Despite intense research, little attention has been paid to scytophycin‐induced cell death or the structural features affecting its… read more here.
Keywords: hydroxyl substitution; potency; effect; new insights ... See more keywords
New Insights Into Intestinal Failure–Associated Liver Disease in Children
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31152
Abstract: Development of intestinal failure–associated liver disease (IFALD) is a common complication of long‐term parenteral nutrition (PN) in children and adults. The molecular and cellular mechanisms and the phases of IFALD are now being delineated. Components… read more here.
Keywords: failure associated; associated liver; intestinal failure; new insights ... See more keywords
The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24383
Abstract: Different pathogenic variants in the fibrillin‐1 gene (FBN1) cause Marfan syndrome and acromelic dysplasias. Whereas the musculoskeletal features of Marfan syndrome involve tall stature, arachnodactyly, joint hypermobility, and muscle hypoplasia, acromelic dysplasia patients present with… read more here.
Keywords: insights focus; fibrillinopathies new; focus paradigm; fbn1 fbn2 ... See more keywords
OCT layered tomography of the cornea provides new insights on remodeling after photorefractive keratectomy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biophotonics"
DOI: 10.1002/jbio.201700027
Abstract: OCT (optical coherence tomography) of corneal layers was generated to analyze the remodeling of the epithelium and stroma after photorefractive keratectomy (PRK). Myopic PRK was performed in 15 patients. One eye underwent manual scraping of… read more here.
Keywords: photorefractive keratectomy; layered tomography; oct layered; prk ... See more keywords
New insights into the role of microRNAs and long noncoding RNAs in most common neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28361
Abstract: Neurodegenerative diseases (NDs) are a diversity of neurological disorders characterized by the progressive degeneration of the structure and function of the central nervous system (CNS). The most common NDs are Alzheimer's disease (AD), Parkinson's disease… read more here.
Keywords: long noncoding; insights role; common nds; neurodegenerative diseases ... See more keywords
New insights into cellular links between sodium–glucose cotransporter‐2 inhibitors and ketogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30327
Abstract: Sodium–glucose cotransporter‐2 inhibitors (SGLT2is) are a newly developed class of highly effective antidiabetic therapies that normalize hyperglycemia via urinary glucose excretion. However, they may be accompanied by certain side effects that negatively impact their therapeutic… read more here.
Keywords: glucose cotransporter; insights cellular; cotransporter inhibitors; sodium glucose ... See more keywords
New insights into the cellular makeup and progenitor potential of palatal connective tissues
Sign Up to like & getrecommendations! Published in 2017 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.22925
Abstract: The present study investigated the regenerative potential of connective tissues harvested from two palatal areas widely used as donor sites for muco‐gingival surgical approaches. Connective tissue grafts (CTGs) were obtained by de‐epithelialisation of a free… read more here.
Keywords: cell lines; insights cellular; connective tissues; new insights ... See more keywords
New insights into the pathophysiology of methylmalonic acidemia
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12617
Abstract: Methylmalonic acidemia (MMA) is a severe inborn error of metabolism that is characterized by pleiotropic metabolic perturbations and multiorgan pathology. Treatment options are limited and non‐curative as the underlying causative molecular mechanisms remain unknown. While… read more here.
Keywords: pathophysiology methylmalonic; methylmalonic acidemia; acidemia; insights pathophysiology ... See more keywords